Carboxyglutamate

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name

Carboxyglutamate

Systematic (IUPAC) name
3-aminopropane-1,1,3-tricarboxylic acid
Identifiers
PubChem         40772
Chemical data
Formula C6H9NO6 
Molar mass 191.139
SMILES C(C(C(=O)O)C(=O)O)C(C(=O)O)N
Complete data

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γ-carboxyglutamate is an uncommon amino acid introduced into proteins by a post-translational carboxylation of glutamate. This modification is found, for example, in clotting factors and other proteins of the coagulation cascade. This modification introduces an affinity for calcium ions.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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