Gastrin releasing peptide
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| gastrin-releasing peptide
| |
| Identifiers | |
| Symbol | GRP |
| Entrez | 2922 |
| HUGO | 4605 |
| OMIM | 137260 |
| RefSeq | NM_001012512 |
| UniProt | P07492 |
| Other data | |
| Locus | Chr. 18 q21.1-21.32 |
Gastrin releasing peptide (GRP) is released by the post-ganglionic fibres of the vagus nerve which innervate the G cells of the stomach and stimulate them to release gastrin. GRP is also involved in the biology of the circadian system, playing a role in the signalling of light to the master circadian oscillator in the suprachiasmatic nuclei of the hypothalamus. Furthermore GRP seems to mediate certain aspects of stress.
This is the reason for the observed fact that atropine does not block the vagal effect on gastrin release.
See also
External links
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Peptides: neuropeptides | |
|---|---|
| Hypothalamic | Somatostatin - CRH - GnRH - GHRH - Orexins - TRH - POMC (ACTH, MSH, Lipotropin) |
| Gastrointestinal hormones | Cholecystokinin - Gastric inhibitory polypeptide - Gastrin - Motilin - Secretin - Vasoactive intestinal peptide |
| Other hormones | Vasopressin - Calcitonin - |
| Other | Angiotensin - Bombesin/Neuromedin B - Calcitonin gene-related peptide - Carnosine - Delta sleep-inducing peptide - FMRFamide - Galanin - Gastrin releasing peptide - Kinins (Bradykinin, Tachykinins ) - Neuromedin (B, N, U) - Neuropeptide Y - Neurophysins - Neurotensin - Opioid peptide - Pancreatic polypeptide - Pituitary adenylate cyclase activating peptide |
Hormones: gastrointestinal hormones |
|---|
| CCK - EGF - GIP - Gastrin releasing peptide - Gastrins - Proglucagon - Motilin - Peptide YY -Prokineticin - Secretin - VIP |
it:Peptide rilasciante la gastrina
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
