Glucose-1-phosphate
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| Glucose-1-phosphate | |
|---|---|
| Image:Cori ester.svg | |
| Image:Cori ester.gif | |
| Identifiers | |
| CAS number | |
| PubChem | |
| MeSH | |
| Properties | |
| Molecular formula | C6H13O9P |
| Molar mass | 260.136 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon.
Reactions
Catabolic
In glycogenolysis, it is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure.
To be utilized in cellular catabolism it must first be converted to glucose 6-phosphate by the enzyme phosphoglucomutase. One reason that cells form glucose-1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell mebrane and so is marked for intracellular catabolism.
Anabolic
In glycogenesis, free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. It can then return to the greater glycogen structure via glycogen synthase.
See also
External links
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