Gummatous

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The classic lesion is the gumma, a granulomatous lesion thought to be caused by reaction to spirochaete in the tissue. Usually found on the face, trunk or extremities, although any organ can be affected. A firm, necrotic center surrounded by inflamed tissue, which forms an amorphous proteinaceous mass with no preserved original architecture. It is restricted to necrosis involving spirochaetal infections (i.e. spirochetes) that cause syphilis.) Gammatous lesions are usually associated with long-term syphilic infection (Source: http://www.thefreedictionary.com/Gumma); however, such lesions can also be a symptom of benign late syphilis.

The formation of gummata is rare in developed countries, but are common in peripheral areas where medical treatment is sub-par.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .