HLA-A11

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major histocompatibility complex (human), class I, A11
Alleles A*1101
A*1102
A*1103
A*1104
Structure (See HLA-A)
Identifiers
*1101 *1102 *1103 *1104
Symbol(s) HLA-A
EBI-HLA A*1101
EBI-HLA A*1102
EBI-HLA A*1103
EBI-HLA A*1104
Shared data
Locus chr.6 6p21.31

HLA-A11 (A11) is an HLA-A serotype. The serotype identifies the more common HLA-A*11 gene products. A11 is more common in eastern Asia particularly along the coastal regions of china.


Serotype

A11 serotype recognition of Some HLA A*11 allele-group gene products[1]
A*11 A11 A10 Sample
allele  %  % size (N)
*1101 99 2530
*1102 76 42
*1103 83 18
*1104 60 6
*1105 66 33 3


Serotyping of A11 demostrates better recognition of the *1101 gene products and poorer recognition of other A*11 gene products. Ther are ~40 recognized alleles of A*11. There is only one null classified as A11.

Disease Associations

By allele

A*1104 is associated with increased risk for cervical neoplasia resulting from human papillomavirus infection[2]


A11-B Haplotypes

A11-B13

  • A11-Cw2-B13 (Li)
  • A11-Cw9-B13 (Southern China & SE Asia)
  • A11-C10-B13 Buyi
  • A11-CBL-B13 Northern China

References

  1. derived from IMGT/HLA
  2. Chan D, Cheung T, Tam A, Cheung J, Yim S, Lo K, Siu N, Zhou D, Chan P (2005). "Risk association between human leukocyte antigen-A allele and high-risk human papillomavirus infection for cervical neoplasia in Chinese women.". J Infect Dis 192 (10): 1749-56. PMID 16235173.
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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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