HLA-A26

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major histocompatibility complex (human), class I, A26
Alleles	A*2601 A*2602 A*2603 A*2605
Structure (See HLA-A)
Identifiers	2601 2602 2603 2605
Symbol(s)	HLA-A
EBI-HLA	A*2601
EBI-HLA	A*2602
EBI-HLA	A*2603
EBI-HLA	A*2605
Shared data
Locus	chr.6 6p21.31

HLA-A26 (A26) is an HLA-A serotype. The serotype identifies the more common HLA-A*26 gene products. A26 is a split antigen of the A10 broad antigen serotype group. A*2601 is believed to be the ancestral type for the A10 group, this group also includes A25, A34, A43 and A66.[1] A26 is broadly distributed but A26 is unusually common in Japan with a number of variants.

Serotype

A26 and A10 serotype recognition of Some HLA A*26 allele-group gene products^[1]

A*26	A26	A10	Sample
allele	%	%	size (N)
2601	97	2	1730
2602	81		31
2603	68	8	38
2605	90		10

Serotype recognition of most alleles is generally good.

Disease associations

A26 Serotype is associated with adult T-cell leukemia in Japanese.^[1][1]

References

v • d • e HLA-A Serotypes
HLA-A - A1 - A2 - A3 - A9 (A23 - A24) - A10 (A25 - A26 - A34 - A43 - A66) - A11 - A19 (A29 - A30 - A31 - A32 - A33 - A74) - A28 (A68 - A69) - A36 - A80

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .