HLA-A43

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major histocompatibility complex (human), class I, A43
Alleles A*4301
Structure (See HLA-A)
Symbol(s) HLA-A
EBI-HLA A*4301
Locus chr.6 6p21.31

HLA-A43 (A43) is an HLA-A serotype. The serotype identifies the more common HLA-A*43 gene products. A43 is a split antigen type of the A10 broad antigen type. A*4301 is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele.[1] A43 is more common in Africa. A*4301 is rare.

Serotype

A26 serotype recognition of Some HLA A*4301 allele gene products[2]
A*43 --- A26 Sample
allele  %  % size (N)
4301 35 9


A43 frequencies

HLA A*4301 frequencies
freq
ref. Population (%)
[3] South Africa Tswana4.9
[3] South Africian Natal Zulu3.0
[3] China Yunnan Han1.2
[3] Zambia Lusaka1.2
[3] Pakistan Karachi Parsi0.6
[3] India North Delhi0.5
[3] Zimbabwe Harare Shona0.4
[3] Italy0.01
[3] China Shanghai0.002

References

  1. Madrigal JA, Hildebrand WH, Belich MP, et al (1993). "Structural diversity in the HLA-A10 family of alleles: correlations with serology". Tissue Antigens 41 (2): 72-80. PMID 8475492.
  2. derived from IMGT/HLA
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403-7. PMID 12753660.
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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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