HLA-A80
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
| major histocompatibility complex (human), class I, A80
| ||
| Alleles | A*8001 | |
| Structure (See HLA-A) | ||
| Identifiers | 8001
| |
| Symbol(s) | HLA-A | |
| EBI-HLA | A*8001 | |
| Locus | chr.6 6p21.31 | |
HLA-A80 (A80) is the least common HLA-A group. The serotype identifies the more common HLA-A*8001 gene product. A80 is almost exclusively found in africa and recent immigrants groups from West Africa
Serotype
| A*80 | A80 | A10 | Sample |
| allele | % | % | size (N) |
| 8001 | 36 | 10 | 505 |
HLA-A80 typing is poor. Most typing is done with SSP-PCR. Most of 8001 are detected
with "Blank" serotype.
Distribution and References
| freq | ||||
| ref. | Population | (%) | ||
| [2] | Bamileke (Cameroon) | 1.9 | ||
| Botswana | 1.8 | |||
| [3] | Fulani (Burkino Faso) | 1.0 | ||
| [2] | Bete(Cameroon) | 0.6 | ||
| Bubi(Eq. Guinea) | 0.5 |
- ↑ derived from IMGT/HLA
- ↑ 2.0 2.1 Torimiro JN, Carr JK, Wolfe ND, et al (2006). "HLA class I diversity among rural rainforest inhabitants in Cameroon: identification of A*2612-B*4407 haplotype". Tissue Antigens 67 (1): 30-7. doi:10.1111/j.1399-0039.2005.00527.x. PMID 16451198.
- ↑ Modiano D, Luoni G, Petrarca V, et al (2001). "HLA class I in three West African ethnic groups: genetic distances from sub-Saharan and Caucasoid populations". Tissue Antigens 57 (2): 128-37. PMID 11260507.
HLA-A Serotypes |
|---|
| HLA-A - A1 - A2 - A3 - A9 (A23 - A24) - A10 (A25 - A26 - A34 - A43 - A66) - A11 - A19 (A29 - A30 - A31 - A32 - A33 - A74) - A28 (A68 - A69) - A36 - A80 |
{
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

