HLA-A80

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major histocompatibility complex (human), class I, A80
Alleles A*8001
Structure (See HLA-A)
Identifiers
8001
Symbol(s) HLA-A
EBI-HLA A*8001
Locus chr.6 6p21.31

HLA-A80 (A80) is the least common HLA-A group. The serotype identifies the more common HLA-A*8001 gene product. A80 is almost exclusively found in africa and recent immigrants groups from West Africa

Serotype

A80 and A10 serotype recognition of Some HLA A*3601 allele-group gene products[1]
A*80 A80 A10 Sample
allele  %  % size (N)
8001 36 10 505

HLA-A80 typing is poor. Most typing is done with SSP-PCR. Most of 8001 are detected with "Blank" serotype.

Distribution and References

HLA A*8001 frequencies
freq
ref. Population (%)
[2] Bamileke (Cameroon) 1.9
Botswana 1.8
[3] Fulani (Burkino Faso) 1.0
[2] Bete(Cameroon) 0.6
Bubi(Eq. Guinea) 0.5
  1. derived from IMGT/HLA
  2. 2.0 2.1 Torimiro JN, Carr JK, Wolfe ND, et al (2006). "HLA class I diversity among rural rainforest inhabitants in Cameroon: identification of A*2612-B*4407 haplotype". Tissue Antigens 67 (1): 30-7. doi:10.1111/j.1399-0039.2005.00527.x. PMID 16451198.
  3. Modiano D, Luoni G, Petrarca V, et al (2001). "HLA class I in three West African ethnic groups: genetic distances from sub-Saharan and Caucasoid populations". Tissue Antigens 57 (2): 128-37. PMID 11260507.
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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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