HLA-A9
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
HLA-A9 (A9) is a broad antigen HLA-A serotype that recognized the HLA-A23 and HLA-A24 serotypes[1]. A*2402 appears to have evolved from A*23 alleles by a process of gene conversion. The A23 is more common in Africa and regions proximal to Africa. A24 is at very high frequencies in Austronesia and certain indigenous peoples of the Arctic[2][3][4], North America[5], South America[6] and West Pacific Rim. While it is common over most of eurasia, it is found at low abundance in NW Europe. A24 appears to have been carried by the first colonizers of South Eastern Asia.
| Split antigen serotypes
of A9 HLA-A |
| HLA-A23 |
| HLA-A24 |
References
- ↑ Fussell H, Thomas M, Street J, Darke C (1996). "HLA-A9 antibodies and epitopes". Tissue Antigens 47 (4): 307-12. PMID 8773320.
- ↑ Lou H, Li HC, Kuwayama M, et al (1998). "HLA class I and class II of the Nivkhi, an indigenous population carrying HTLV-I in Sakhalin, Far Eastern Russia". Tissue Antigens 52 (5): 444-51. PMID 9864034.
- ↑ Nelson JL, Boyer G, Templin D, et al (1992). "HLA antigens in Tlingit Indians with rheumatoid arthritis". Tissue Antigens 40 (2): 57-63. PMID 1412417.
- ↑ Welinder L, Graugaard B, Madsen M (2000). "HLA antigen and gene frequencies in Eskimos of East Greenland". Eur. J. Immunogenet. 27 (2): 93-7. PMID 10792425.
- ↑ Leffell MS, Fallin MD, Hildebrand WH, Cavett JW, Iglehart BA, Zachary AA (2004). "HLA alleles and haplotypes among the Lakota Sioux: report of the ASHI minority workshops, part III". Hum. Immunol. 65 (1): 78-89. PMID 14700599.
- ↑ Fleischhauer K, Agostino A, Zino E, et al (1999). "Molecular characterization of HLA class I in Colombians carrying HLA-A2: high allelic diversity and frequency of heterozygotes at the HLA-B locus". Tissue Antigens 53 (6): 519-26. PMID 10395101.
HLA-A Serotypes |
|---|
| HLA-A - A1 - A2 - A3 - A9 (A23 - A24) - A10 (A25 - A26 - A34 - A43 - A66) - A11 - A19 (A29 - A30 - A31 - A32 - A33 - A74) - A28 (A68 - A69) - A36 - A80 |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
