HLA-B59

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major histocompatibility complex (human), class I, B59
Alleles	B*5901
Structure (See HLA-B)
Symbol(s)	HLA-B
EBI-HLA	B*5901
Locus	chr.6 6p21.31

HLA-B59 (B59) is an HLA-B serotype. The serotype identifies the more common HLA-B*## gene products.^[1] B59 is a hybrid between B*55 and B*51.^[1] B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: HLA-serotype tutorial)

Serotype

B59 serotype recognition of the HLA B*59 allele-group gene products^[1]

B*59	B59	Other	Sample
allele	%	%	size (N)
5901	45	41	123

B*5901 allele frequencies

HLA B*5901 frequencies

		freq
ref.	Population	(%)
[1]	Okinawan (USA Hawaii)	6.3
[1]	Japan (2)	2.7
[1]	Tarialan Khoton (Mongolia)	2.4
[1]	South Korea (3)	2.1
[1]	Gipuscoa Basque (Spain)	2.0
[1]	Japan Central	1.8
[1]	Casablanca (Morocco)	1.8
[1]	Hyogo (Japan)	1.6
[1]	N. Korean (Harbin,China)	1.0
[1]	Manchu (Harbin, China)	0.6
[1]	Naxi (Yunnan, China)	0.6
[1]	Girona (Catalonia,Spain)	0.6
[1]	Algeria (1)	0.5
[1]	Inner Mongolia (China)	0.5
[1]	Khalkha (Mongolia)	0.5
[1]	Shanghai (China)	0.3
[1]	Essen (German )	0.3
[1]	Southern Han (China)	0.2
[1]	Shij. Tian. (Beijing, China)	0.1
[1]	Hakka (Taiwan)	0.1

Regions of higher B*5901 frequency

Japan
Korea
Mongolia
Heilongjiang prov., China (Harbin city)

References

v • d • e HLA-B Serotypes and allele groups
HLA-B - B5 (B51 - B52) - B7 - B8 - B12 (B44 - B45) - B13 - B14]] (B64 - B65) - B15 (B62 - B63 - B70 - B71- B75 - B76 - B77) - B16 (B38 - B39) - B17 (B57 - B58) - B18 - B21 (B49 - B50) - B22 (B54 - B55 - B56) - B27 - B35 - B37 - B40 (B60 - B61) - B41 - B42 - B46 - B47 - B48 - B53 - B59 - B67 - B73 - B78 - B81 - B*82 - B*83

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .