Hamman-Rich syndrome

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HR syndrome Classification and external resources
ICD-10	J84.1
ICD-9	516.3
OMIM	178500
DiseasesDB	4815

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Hamman-Rich syndrome (also known as acute interstitial pneumonia) is a rare, severe lung disease which usually affects otherwise healthy individuals.

HR syndrome is often categorized as both an interstitial lung disease and a form of acute respiratory distress syndrome (ARDS).

Symptoms

The most common symptoms of Hamman-Rich syndrome are cough, fever, and difficulties breathing. These often occur over a period of one to two weeks before medical attention is sought. Difficulties breathing can quickly progress to an inability to breathe without support (respiratory failure).

Hamman-Rich syndrome typically progresses rapidly, with hospitalization and mechanical ventilation often required only days to weeks after initial symptoms of cough, fever, and difficulties breathing develop.

Diagnosis

Rapid progression from initial symptoms to respiratory failure is a key feature of Hamman-Rich syndrome. An x-ray which shows ARDS is necessary for diagnosis (fluid in the small air sacs (alveoli) in both lungs). In addition, a biopsy of the lung which shows organizing diffuse alveolar damage is required for diagnosis. Other diagnostic tests are useful excluding other similar condition, but history, x-ray, and biopsy are necessary. These other tests may include basic blood work, blood cultures, and bronchoalveolar lavage.

Treatment

Treatment of HR syndrome is primarily supportive. Management in an intensive care unit is required and the need for mechanical ventilation is common. Therapy with corticosteroids is generally attempted, though their usefulness has not been established as of 2005.

Epidemiology

HR syndrome occurs most frequently among people older than forty years old. It affects men and women equally. There are no known risk factors; in particular, smoking is not associated with increased risk.

Prognosis

Sixty percent of people with HR syndrome will die in the first six months of illness. However, most people who have one episode do not have a second. People who survive often recover lung function completely.

History

HR syndrome was first described in 1935 by Louis Hamman and Arnold Rich.

References

1. ^  HR, AR. Fulminating diffuse interstitial fibrosis of the lungs. Trans Am Clin Climatol Assoc 1935; 51:154.

External links

• synd/3010 at Who Named It
• 00181 at CHORUS
• 1241907254 at GPnotebook
• LUN100 at FPnotebook

v • d • e Pathology of respiratory system (J, 460-519), respiratory diseases
Upper RT (including URTIs, Common cold)	Head sinuses: Sinusitis nose: Rhinitis (Vasomotor rhinitis, Atrophic rhinitis, Hay fever) - Nasal polyp - Deviated septum tonsil: Tonsillitis - Adenoid hypertrophy - Peritonsillar abscess Neck pharynx: Pharyngitis (Strep throat) larynx: Laryngitis - Croup - Laryngospasm - vocal folds: Vocal fold nodule - epiglottis: Epiglottitis trachea: Tracheitis - Tracheal stenosis
Lower RT/lung disease (including LRTIs)	Pneumonia Viral - Bacterial/Atypical pneumonia (Mycoplasma) - Fungal pneumonia (Pneumocystis pneumonia) - Parasitic pneumonia - Bronchopneumonia - Chemical pneumonia (Mendelson's syndrome) Bronchial/ obstructive Acute: Bronchitis (Acute, Chronic) - Bronchiolitis Chronic: Emphysema - COPD - Asthma (Status asthmaticus) - Diffuse panbronchiolitis - Bronchiectasis Interstitial/ restrictive External agents/ occupational lung disease Pneumoconiosis (Asbestosis, Baritosis, Bauxite fibrosis, Berylliosis, Caplan's syndrome, Chalicosis, Coalworker's pneumoconiosis, Siderosis, Silicosis, Byssinosis) Hypersensitivity pneumonitis (Bagassosis, Bird fancier's lung, Farmer's lung) Other ARDS - Pulmonary edema - Löffler's syndrome/Eosinophilic pneumonia - Respiratory hypersensitivity (Allergic bronchopulmonary aspergillosis) Hamman-Rich syndrome - Idiopathic pulmonary fibrosis Obstructive or restrictive Atelectasis - Bronchiolitis obliterans
Pleural cavity/mediastinum	Suppuration Empyema - Lung abscess Pleural disease/pleural effusion Hemothorax - Pneumothorax (Tension pneumothorax) - Hemopneumothorax - Hydrothorax - Chylothorax - Pleurisy Mediastinal disease Mediastinal emphysema - Mediastinitis
Other/general	Respiratory failure - Influenza - SARS - Idiopathic pulmonary haemosiderosis
see also congenital, neoplasia

v • d • e WikiDoc Research Resources for Hamman-Rich syndrome
Articles on Hamman-Rich syndrome	Most recent articles on Hamman-Rich syndrome • Most cited articles on Hamman-Rich syndrome • Review articles on Hamman-Rich syndrome • Articles on Hamman-Rich syndrome in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Hamman-Rich syndrome	Powerpoint slides on Hamman-Rich syndrome • Images of Hamman-Rich syndrome • Photos of Hamman-Rich syndrome • Podcasts & MP3s on Hamman-Rich syndrome • Videos on Hamman-Rich syndrome
Evidence Based Medicine Regarding Hamman-Rich syndrome	Cochrane Collaboration on Hamman-Rich syndrome • Bandolier on Hamman-Rich syndrome • TRIP on Hamman-Rich syndrome
Cost Effectiveness of Hamman-Rich syndrome	Cost Effectiveness of Hamman-Rich syndrome
Clinical Trials Involving Hamman-Rich syndrome	Ongoing Trials on Hamman-Rich syndrome at Clinical Trials.gov • Trial results on Hamman-Rich syndrome • Clinical Trials on Hamman-Rich syndrome at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Hamman-Rich syndrome	US National Guidelines Clearinghouse on Hamman-Rich syndrome • NICE Guidance on Hamman-Rich syndrome • NHS PRODIGY Guidance • FDA on Hamman-Rich syndrome • CDC on Hamman-Rich syndrome
Textbook Information on Hamman-Rich syndrome	Books and Textbook Information on Hamman-Rich syndrome
Pharmacology Resources on Hamman-Rich syndrome	Dosing of Hamman-Rich syndrome • Drug interactions with Hamman-Rich syndrome • Side effects of Hamman-Rich syndrome • Allergic reactions to Hamman-Rich syndrome • Overdose information on Hamman-Rich syndrome • Carcinogenicity information on Hamman-Rich syndrome • Hamman-Rich syndrome in pregnancy • Pharmacokinetics of Hamman-Rich syndrome •
Genetics, Pharmacogenomics, and Proteinomics of Hamman-Rich syndrome	Genetics of Hamman-Rich syndrome • Pharmacogenomics of Hamman-Rich syndrome • Proteomics of Hamman-Rich syndrome
Newstories on Hamman-Rich syndrome	Hamman-Rich syndrome in the news • Be alerted to news on Hamman-Rich syndrome • News trends on Hamman-Rich syndrome
Commentary on Hamman-Rich syndrome	Blogs on Hamman-Rich syndrome
Patient Resources on Hamman-Rich syndrome	Patient resources on Hamman-Rich syndrome • Discussion groups on Hamman-Rich syndrome • Patient Handouts on Hamman-Rich syndrome • Directions to Hospitals Treating Hamman-Rich syndrome • Risk calculators and risk factors for Hamman-Rich syndrome
Healthcare Provider Resources on Hamman-Rich syndrome	Symptoms of Hamman-Rich syndrome • Causes & Risk Factors for Hamman-Rich syndrome • Diagnostic studies for Hamman-Rich syndrome • Treatment of Hamman-Rich syndrome
Continuing Medical Education (CME) Programs on Hamman-Rich syndrome	CME Programs on Hamman-Rich syndrome
International Resources on Hamman-Rich syndrome	Hamman-Rich syndrome en Espanol • Hamman-Rich syndrome en Francais
Business Resources on Hamman-Rich syndrome	Hamman-Rich syndrome in the Marketplace • Patents on Hamman-Rich syndrome
Informatics Resources on Hamman-Rich syndrome	List of terms related to Hamman-Rich syndrome

de:Akute interstitielle Pneumonie

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .