Hemolytic disease of the newborn (anti-RhE)

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HDN due to anti-RhE alloimmunization
Classification and external resources
ICD-10 P55.8
ICD-9 773.2

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Hemolytic disease of the newborn (anti-RhE)

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Hemolytic disease of the newborn (anti-RhE) is caused by the anti-RhE antibody of the Rhesus blood group system. The anti-RhE antibody can be naturally occurring, or arise following immune sensitization after a blood transfusion or pregnancy.

The anti-RhE antibody is quite common especially in the Rhesus genotype CDe/CDe; it can occasionally cause mild jaundice in the neonate, but it never causes severe haemolytic disease of the newborn. It can occur with other antibodies, usually the anti-Rhc antibody, which can cause a severe hemolytic disease.

References

  • Antenatal & neonatal screening (second edition). Chapter 12: Rhesus and other haemolytic diseases, by E.A. Letsky, I. Leck, J.M. Bowman. 2000. Oxford University Press. ISBN 0-19-262827-7.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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