Human mitochondrial DNA haplogroup
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In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. These haplogroups have led some researchers to trace the matrilineal inheritance of modern humans back to human origins in Africa and the subsequent spread across the globe.
Known haplogroups are assigned the following letter codes: A, B, C, CZ, D, E, F, G, H, pre-HV, HV, I, J, pre-JT, JT, K, L0, L1, L2, L3, L4, L5, L6, L7, M, N, O, P, Q, R, S, T, U, UK, V, W, X, Y, and Z.
The woman who is at the root of all these groups is the most recent common matrilineal (female-lineage) ancestor of all living humans. She is commonly called Mitochondrial Eve.
Evolutionary relationship
Precise evolutionary relationships between human mitochondrial haplogroups are subject to academic debate.
L0L1 and its descendants
Descendants of haplogroup L3Descendants of haplogroup M*
Descendants of haplogroup N*
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Descendants of haplogroup R
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Table form
Other forms
For a graphical depiction of haplogroup branching, see Vincent Macaulay's mtDNA haplogroup skeleton.
For information on the mutations which characterize each haplogroup, see the table of mtDNA haplogroup motifs.
See also
- Human mitochondrial genetics
- Cambridge Reference Sequence
- Human Y-chromosome DNA haplogroup
- * (haplogroup)
- Molecular phylogeny
- Genetic genealogy
- Genealogical DNA test
- Hypervariable region
References
- ^ Mitochondrial haplogroup skeleton, by Vincent Macaulay
- ^ Mitochondrial haplogroup motifs, by Vincent Macaulay
External links
- mtDNA .pdf map
- Map of macro-haplogroup N by John S. Walden
- Indian maternal gene pool, Journal of Human Genetics
- The Making of the African mtDNA Landscape, American Journal of Human Genetics
- Do the Four Clades of the mtDNA Haplogroup L2 Evolve at Different Rates?, American Journal of Human Genetics
- The Matrilineal Ancestry of Ashkenazi Jewry: Portrait of a Recent Founder Event, American Journal of Human Geneticsca:Haplogrups mitocondrials humans
cs:Haploskupiny lidské mitochondriální DNA
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
