Hurthle cell
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| Hurthle cell Classification and external resources | |
| ICD-10 | C73.9 |
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| ICD-O: | 8290/0 |
| DiseasesDB | 31956 |
| eMedicine | med/1045 |
| MeSH | D018249 |
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Overview
A Hürthle cell (also known as Askanazy cell) is an oncocytic cell in the thyroid that is often associated with Hashimoto's thyroiditis as well as follicular thyroid cancer. Hürthle cells are characterized as enlarged epithelial cells with abundant eosinophilic granular cytoplasm as a result of altered mitochondria.[1] They generally stain pink and are prominently found in histological sections of thyroid glands affected with Hashimoto's.
A Hürthle cell adenoma is a well-differentiated type of follicular thyroid adenoma (benign tumor) that, in rare cases, has the potential to metastasize and become malignant (Hürthle cell carcinoma).
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
