Inner membrane
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The inner membrane is the cell membrane (phospholipid bilayer) of an organelle or Gram-negative bacteria that is within an outer membrane.
In eukaryotic cells, this inner membrane is present within the nuclear envelope, mitochondria and plastids like the chloroplast. The lumen between the inner and outer membranes is referred to as intermembrane space.
In prokaryotic cells such as many Gram-negative bacteria, the space between the inner and outer membrane is commonly referred to as the periplasmic space or periplasm. The inner membrane may also be referred to as the cytoplasmic membrane and it is similar in structure and protein content as the cytoplasmic membrane of other bacteria that contain only one membrane (such as most Gram-positive bacteria).
This structural arrangement of an inner and outer membrane is throught to be similar in Gram-negative bacteria, mitochondria and chloroplasts due to their ancestral relationship, as outlined in the endosymbiotic theory.
Inner membrane of the nuclear envelope
The inner membrane of the nuclear envelope is connected to the outer nuclear envelope membrane through nuclear pores. It contains a number of proteins involved in the structural organization of the nucleus and the attachment of chromatin to the nuclear envelope. In metazoan cells, the inner nuclear membrane contains proteins of the nuclear lamina, a protein meshwork underlying the nuclear envelope and providing structural support. Mutations in inner nuclear envelope proteins can cause nuclear envelopathies, a number of genetic disorders in humans.
Mitochondrial inner membrane
- See main article at Inner mitochondrial membrane
The mitochondrial inner membrane forms internal compartments known as cristae, which allow greater space for the proteins such as cytochromes to function properly and efficiently.
Plastidial inner membrane
The plastidial inner membrane surrounds the stroma of the plastid. In chloroplasts, extensions of the inner membrane form the thylakoid membrane where the photosystems for photosynthesis are located. The inner and thylakoid membranes are very similar to the membranes found in cyanobacteria. Similar to mitochondria, plastids are thought to have evolved from bacterial endosymbionts.
See also
For eukaryotes
For bacteria
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
