Inorganic pyrophosphatase
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| pyrophosphatase (inorganic) 1
| |
| Identifiers | |
| Symbol | PPA1 |
| Alt. Symbols | PP |
| Entrez | 5464 |
| HUGO | 9226 |
| OMIM | 179030 |
| RefSeq | NM_021129 |
| UniProt | Q15181 |
| Other data | |
| EC number | 3.6.1.1 |
| Locus | Chr. 10 q11.1-q24 |
| pyrophosphatase (inorganic) 2
| |
| Identifiers | |
| Symbol | PPA2 |
| Entrez | 27068 |
| HUGO | 28883 |
| OMIM | 609988 |
| RefSeq | NM_176869 |
| UniProt | Q9H2U2 |
| Other data | |
| Locus | Chr. 4 q25 |
Pyrophosphatase (or inorganic pyrophosphatase) is an enzyme that converts one molecule of pyrophosphate to two phosphate ions. This highly exergonic reaction (about -34KJ change in free energy) can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion, as in Lipid synthesis and other biochemical transformations.
External links
Hydrolases: acid anhydride hydrolases (EC 3.6) | |
|---|---|
| 3.6.1 | Pyrophosphatase (Inorganic, Thiamine) - Apyrase - Thiamine triphosphatase |
| 3.6.3-4 | ATPase |
| 3.6.5 | GTPase |
Ion pump: proton pumps | |
|---|---|
| ETC | ETC Complex I - ETC Complex III - ETC Complex IV |
| Other | Bacteriorhodopsin - Cytochrome b6f complex - Inorganic pyrophosphatase - V-ATPase |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
