Interneuron
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| Interneuron | |
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| The mechanism of the reflex arc. (Relay neuron labeled at right center. Diagram discusses the PNS definition.) | |
| MeSH | Interneurons |
| Dorlands/Elsevier | i_10/12455676 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
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Overview
An interneuron (also called relay neuron, association neuron or bipolar neuron) is a term used to describe a neuron which has two different common meanings.
PNS
In the peripheral nervous system, an interneuron is a neuron that communicates only to other neurons. Interneurons are the neurons that provide connections between sensory and motor neurons, as well as between themselves. Contrast to sensory neurons or motor neurons, which respectively provide input from and output to the rest of the body.
Interneurons are found in the grey matter. One type of peripheral interneuron is the Renshaw cell.
CNS
According to the PNS definition, the neurons of the central nervous system, including the brain, are all interneurons. However, in the CNS, the term interneurons is also used for the general group of small, locally projecting neurons of the central nervous system. These neurons are typically inhibitory, and use the neurotransmitter GABA. However, excitatory interneurons also exist.
One example of interneurons are inhibitory interneurons in the neocortex which selectively inhibit sections of the thalamus based on synaptic input both from other parts of the neocortex and from the thalamus itself. This is theorized to help focus higher attention on relevant sensory input and help block out behavioraly irrelevant or unchanging input, such as the sensation of the backs of your thighs on a chair. A human brain contains about 100 billion interneurons.
External links
- Interneurons at eMedicine Dictionary
Histology: nervous tissue | |
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| Neurons (gray matter) | soma - axon (axon hillock, axoplasm, axolemma, neurofibril/neurofilament)
dendrite (Nissl body, dendritic spine, apical dendrite, basal dendrite) types: bipolar - pseudounipolar - multipolar - pyramidal - Purkinje - granule |
| Afferent nerve/Sensory nerve/Sensory neuron | GSA - GVA - SSA - SVA - fibers (Ia, Ib or Golgi, II or Aβ, III or Aδ or fast pain, IV or C or slow pain) |
| Efferent nerve/Motor nerve/Motor neuron | GSE - GVE - SVE - Upper motor neuron - Lower motor neuron (α motorneuron, γ motorneuron) |
| Synapses | neuropil - synaptic vesicle - neuromuscular junction - electrical synapse - Interneuron (Renshaw) |
| Sensory receptors | Meissner's corpuscle - Merkel nerve ending - Pacinian corpuscle - Ruffini ending - Muscle spindle Olfactory receptor neuron - Photoreceptor cell - Hair cell - Taste bud |
| Glial cells | Astrocyte (Radial glia) - Oligodendrocyte - Ependymal cells (Tanycytes) - Microglia |
| Myelination (white matter) | CNS: Oligodendrocyte PNS: Schwann cell - Neurolemma - Nodes of Ranvier/Internode - Schmidt-Lanterman incisures |
| Related connective tissues | epineurium - perineurium - endoneurium - nerve fascicle - meninges |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
