Lentigo maligna melanoma
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| Lentigo maligna melanoma Classification and external resources | |
| ICD-O: | 8742 |
|---|---|
| DiseasesDB | 32059 |
| eMedicine | med/1278 |
| MeSH | D018327 |
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Overview
Lentigo maligna is a melanoma in situ: it consists of malignant cells but does not show invasive growth. It can remain in this non-invasive form for years. It is normally found in the elderly (peak incidence in the 9th decade), on skin areas with high levels of sun exposure (for example, face and forearms). When it develops into melanoma, the resulting lesion is called lentigo maligna melanoma. The transition to melanoma is marked by the appearance of a bumpy surface (vertical growth, invasion).
Treatment
Therapy of lentigo maligna consists of surgical excision (best) or radiotherapy (only in special cases).
Presentation
Characteristics include blue/black stain of skin initially. Skin is thin- about 4-5 cell layers thick. ( often due to aging). This tumor is also a slow progressive one.
Histological features include: epidermal atrophy and increase number of melanocytes.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
