Letterer-Siwe disease
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| Letterer-Siwe disease Classification and external resources | |
| ICD-10 | C96.0 |
|---|---|
| ICD-9 | 202.5 |
| OMIM | 246400 |
| DiseasesDB | 5906 |
| MeSH | D006646 |
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Letterer-Siwe disease is a condition where histiocytes proliferate in the body. It is sometimes classified as a form of Langerhans cell histiocytosis, or as a disseminated form of histiocytosis X. It is most commonly seen in children less than two years old.
Symptoms include lymphadenopathy, hepatosplenomegaly, and seborrhea-like lesions on the skin. Untreated, the disease is fatal. The five-year survival rate with treatment is fifty percent.
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
