Myeloid leukemia

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Myeloid leukemia Classification and external resources
Blood smear from a patient with untreated CML showing segmented neutrophils, myelocytes, a promyelocyte, and two basophils. (Wright-Giemsa stain) Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology
ICD-10	C92.
ICD-9	205
MeSH	D007951

WikiDoc Resources for Myeloid leukemia
Articles
Most recent articles on Myeloid leukemia Most cited articles on Myeloid leukemia Review articles on Myeloid leukemia Articles on Myeloid leukemia in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Myeloid leukemia Images of Myeloid leukemia Photos of Myeloid leukemia Podcasts & MP3s on Myeloid leukemia Videos on Myeloid leukemia
Evidence Based Medicine
Cochrane Collaboration on Myeloid leukemia Bandolier on Myeloid leukemia TRIP on Myeloid leukemia
Clinical Trials
Ongoing Trials on Myeloid leukemia at Clinical Trials.gov Trial results on Myeloid leukemia Clinical Trials on Myeloid leukemia at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Myeloid leukemia NICE Guidance on Myeloid leukemia NHS PRODIGY Guidance FDA on Myeloid leukemia CDC on Myeloid leukemia
Books
Books on Myeloid leukemia
News
Myeloid leukemia in the news Be alerted to news on Myeloid leukemia News trends on Myeloid leukemia
Commentary
Blogs on Myeloid leukemia
Definitions
Definitions of Myeloid leukemia
Patient Resources / Community
Patient resources on Myeloid leukemia Discussion groups on Myeloid leukemia Patient Handouts on Myeloid leukemia Directions to Hospitals Treating Myeloid leukemia Risk calculators and risk factors for Myeloid leukemia
Healthcare Provider Resources
Symptoms of Myeloid leukemia Causes & Risk Factors for Myeloid leukemia Diagnostic studies for Myeloid leukemia Treatment of Myeloid leukemia
Continuing Medical Education (CME)
CME Programs on Myeloid leukemia
International
Myeloid leukemia en Espanol Myeloid leukemia en Francais
Businness
Myeloid leukemia in the Marketplace Patents on Myeloid leukemia
Experimental / Informatics
List of terms related to Myeloid leukemia

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Overview

Myeloid leukemia is a type of leukemia affecting myeloid tissue (bone marrow).

Types include:

• Acute myelogenous leukemia (AML)
• Chronic myelogenous leukemia (CML)

External links

• The Leukemia & Lymphoma Society
• Blood & Marrow Transplant Information Network
• Association of Cancer Online Resource (ACOR) Leukemia Links
• Merck Manual:Chronic Myelocytic Leukemia (CML)

v • d • e Pathology: hematology, myeloid hematologic disease (primarily D50-D77, 280-289)
RBCs/ hemoglobinopathy	+ Polycythemia - Macrocytosis - Anemia Nutritional Iron deficiency anemia (Plummer-Vinson syndrome), Megaloblastic anemia (Pernicious anemia) Hemolytic Hereditary enzyme: G6PD Deficiency - Pyruvate kinase deficiency - Triosephosphate isomerase deficiency hemoglobin: Thalassemia - Sickle-cell disease/trait membrane: Hereditary spherocytosis - Hereditary elliptocytosis - Hereditary stomatocytosis Acquired Autoimmune (Warm, Cold), HUS, MAHA, PNH, PCH, Myelophthisic Aplastic Acquired PRCA, Diamond-Blackfan anemia, Fanconi anemia, Sideroblastic anemia Blood tests Normocytic - Microcytic - Macrocytic - Normochromic - Hypochromic Other Methemoglobinemia
Coagulation/platelets/ coagulopathy/ bleeding diathesis	+ Hypercoagulability primary: Antithrombin III deficiency - Protein C deficiency/Activated protein C resistance/Protein S deficiency/Factor V Leiden - Hyperprothrombinemia acquired: DIC (Congenital afibrinogenemia, Purpura fulminans) - autoimmune (Antiphospholipid) Other Essential thrombocytosis - clotting factor: Hemophilia (A/VIII, B/IX, C/XI) • Von Willebrand disease • Hypoprothrombinemia/II - XIII platelet function: Bernard-Soulier syndrome - Glanzmann's thrombasthenia - Gray platelet syndrome - May Hegglin anomaly - Pelger-Huet anomaly Purpura: Henoch-Schönlein, ITP (Evans syndrome), TTP Thrombocytopenia (Heparin-induced thrombocytopenia)
Monocytes/ macrophages	+ Histiocytosis WHO-I (Langerhans cell histiocytosis) WHO-II/non-Langerhans-cell (Juvenile xanthogranuloma, Hemophagocytic lymphohistiocytosis) WHO-III/malignant (Acute monocytic leukemia, Malignant histiocytosis, Erdheim-Chester disease) Other Chronic granulomatous disease -cytosis: Monocytosis - -penia: Monocytopenia
Granulocytes	+ -cytosis: granulocytosis (Neutrophilia, Eosinophilia, Basophilia) - -penia: Granulocytopenia/agranulocytosis (Neutropenia/Kostmann syndrome, Eosinopenia, Basopenia)
See also hematological malignancy and immune disorders

v • d • e Pathology: hematology, myeloid hematologic disease (primarily D50-D77, 280-289)
RBCs/ hemoglobinopathy	+ Polycythemia - Macrocytosis - Anemia Nutritional Iron deficiency anemia (Plummer-Vinson syndrome), Megaloblastic anemia (Pernicious anemia) Hemolytic Hereditary enzyme: G6PD Deficiency - Pyruvate kinase deficiency - Triosephosphate isomerase deficiency hemoglobin: Thalassemia - Sickle-cell disease/trait membrane: Hereditary spherocytosis - Hereditary elliptocytosis - Hereditary stomatocytosis Acquired Autoimmune (Warm, Cold), HUS, MAHA, PNH, PCH, Myelophthisic Aplastic Acquired PRCA, Diamond-Blackfan anemia, Fanconi anemia, Sideroblastic anemia Blood tests Normocytic - Microcytic - Macrocytic - Normochromic - Hypochromic Other Methemoglobinemia
Coagulation/platelets/ coagulopathy/ bleeding diathesis	+ Hypercoagulability primary: Antithrombin III deficiency - Protein C deficiency/Activated protein C resistance/Protein S deficiency/Factor V Leiden - Hyperprothrombinemia acquired: DIC (Congenital afibrinogenemia, Purpura fulminans) - autoimmune (Antiphospholipid) Other Essential thrombocytosis - clotting factor: Hemophilia (A/VIII, B/IX, C/XI) • Von Willebrand disease • Hypoprothrombinemia/II - XIII platelet function: Bernard-Soulier syndrome - Glanzmann's thrombasthenia - Gray platelet syndrome - May Hegglin anomaly - Pelger-Huet anomaly Purpura: Henoch-Schönlein, ITP (Evans syndrome), TTP Thrombocytopenia (Heparin-induced thrombocytopenia)
Monocytes/ macrophages	+ Histiocytosis WHO-I (Langerhans cell histiocytosis) WHO-II/non-Langerhans-cell (Juvenile xanthogranuloma, Hemophagocytic lymphohistiocytosis) WHO-III/malignant (Acute monocytic leukemia, Malignant histiocytosis, Erdheim-Chester disease) Other Chronic granulomatous disease -cytosis: Monocytosis - -penia: Monocytopenia
Granulocytes	+ -cytosis: granulocytosis (Neutrophilia, Eosinophilia, Basophilia) - -penia: Granulocytopenia/agranulocytosis (Neutropenia, Kostmann syndrome)
See also hematological malignancy and immune disorders

v • d • e WikiDoc Research Resources for Myeloid leukemia
Articles on Myeloid leukemia	Most recent articles on Myeloid leukemia • Most cited articles on Myeloid leukemia • Review articles on Myeloid leukemia • Articles on Myeloid leukemia in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Myeloid leukemia	Powerpoint slides on Myeloid leukemia • Images of Myeloid leukemia • Photos of Myeloid leukemia • Podcasts & MP3s on Myeloid leukemia • Videos on Myeloid leukemia
Evidence Based Medicine Regarding Myeloid leukemia	Cochrane Collaboration on Myeloid leukemia • Bandolier on Myeloid leukemia • TRIP on Myeloid leukemia
Cost Effectiveness of Myeloid leukemia	Cost Effectiveness of Myeloid leukemia
Clinical Trials Involving Myeloid leukemia	Ongoing Trials on Myeloid leukemia at Clinical Trials.gov • Trial results on Myeloid leukemia • Clinical Trials on Myeloid leukemia at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Myeloid leukemia	US National Guidelines Clearinghouse on Myeloid leukemia • NICE Guidance on Myeloid leukemia • NHS PRODIGY Guidance • FDA on Myeloid leukemia • CDC on Myeloid leukemia
Textbook Information on Myeloid leukemia	Books and Textbook Information on Myeloid leukemia
Pharmacology Resources on Myeloid leukemia	Dosing of Myeloid leukemia • Drug interactions with Myeloid leukemia • Side effects of Myeloid leukemia • Allergic reactions to Myeloid leukemia • Overdose information on Myeloid leukemia • Carcinogenicity information on Myeloid leukemia • Myeloid leukemia in pregnancy • Pharmacokinetics of Myeloid leukemia •
Genetics, Pharmacogenomics, and Proteinomics of Myeloid leukemia	Genetics of Myeloid leukemia • Pharmacogenomics of Myeloid leukemia • Proteomics of Myeloid leukemia
Newstories on Myeloid leukemia	Myeloid leukemia in the news • Be alerted to news on Myeloid leukemia • News trends on Myeloid leukemia
Commentary on Myeloid leukemia	Blogs on Myeloid leukemia
Patient Resources on Myeloid leukemia	Patient resources on Myeloid leukemia • Discussion groups on Myeloid leukemia • Patient Handouts on Myeloid leukemia • Directions to Hospitals Treating Myeloid leukemia • Risk calculators and risk factors for Myeloid leukemia
Healthcare Provider Resources on Myeloid leukemia	Symptoms of Myeloid leukemia • Causes & Risk Factors for Myeloid leukemia • Diagnostic studies for Myeloid leukemia • Treatment of Myeloid leukemia
Continuing Medical Education (CME) Programs on Myeloid leukemia	CME Programs on Myeloid leukemia
International Resources on Myeloid leukemia	Myeloid leukemia en Espanol • Myeloid leukemia en Francais
Business Resources on Myeloid leukemia	Myeloid leukemia in the Marketplace • Patents on Myeloid leukemia
Informatics Resources on Myeloid leukemia	List of terms related to Myeloid leukemia

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .