Leukonychia

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Leukonychia (or Leuconychia) is a medical term for white discoloration appearing on nails. It is derived from the Greek words Leuko white and Onyx nail. The most common cause is injury to the base of the nail (the matrix) where the nail is formed.

Types of Leukonychia

Leukonychia Totalis

This condition is a whitening of the entire nail. This may be due to hypoalbuminaemia, a genetic condition, or a side effect of sulphonamides, a family of antibiotics.^[1]

Leukonychia Partialis

This condition is whitening of parts of the nail. There are several types of this condition.

Leukonychia Striata or Transverse Leukonychia

This is a whitening or discoloration of the nail in bands or "stria". It may be caused by cirrhosis, chemotherapy, or physical injury to the nail matrix. (i.e. excessive nail "tapping" or slamming in a car door).^[1]

This condition looks similar to Mee's lines, a condition caused by Arsenic, Lead, or other heavy metal poisoning.

'True' Leukonychia

This is the most common form of Leukonychia, small white spots on the nails. Picking and biting of the nails are a prominent cause in young children and nail biters. In most cases, when white spots appear on a single or a couple of fingers or toes, the most common cause is injury to the base (matrix) of the nail. When this is the case, white spots disappear after around eight months, which is the amount of time necessary for nails to regrow completely.^[1]

White spots showing up on all or nearly all nails for longer periods of time (months and years) can be due to one of several reasons. One common explanation is zinc deficiency.^[1]

Diagnosis and treatment

A doctor will take a thorough medical history, and may test liver and kidney function. If a zinc deficiency is identified, a diet rich in zinc or zinc supplements may be administered.

References

• Leukonychia Striata information
• Leukonychia Totalis information
• New England Journal of Medicine: Transverse Leukonychia
• Medscape Today: Traumatic Transverse Leukonychia

External links

• The Straight Dope: What causes white spots on your fingernails?

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .