Leukotriene C4 synthase
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| leukotriene C4 synthase
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| Identifiers | |
| Symbol | LTC4S |
| Entrez | 4056 |
| HUGO | 6719 |
| OMIM | 246530 |
| RefSeq | NM_000897 |
| UniProt | Q16873 |
| Other data | |
| EC number | 4.4.1.20 |
| Locus | Chr. 5 q35 |
Leukotriene C4 synthase (or glutathione S-transferase II) is an enzyme which converts leukotriene A4 and glutathione to create leukotriene C4.
A trimer of Leukotriene C4 synthase is localized on the outer nuclear membrane and endoplasmic reticulum where it forms a complex with 5-Lipoxygenase activating protein. This protein is remotely related to microsomal glutathione S-transferase.
External links
MeSH leukotriene-C4+synthase UMich Orientation of Proteins in Membranes families/superfamily-199 - Eicosanoid and Glutathione metabolism protein family (MAPEG)
Carbon-sulfur lyases (EC 4.4) |
|---|
| Cystathionine gamma-lyase - Cystathionine-beta-lyase - Leukotriene C4 synthase |
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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
