List of EC numbers (EC 6)
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This list contains a list of EC numbers for the sixth group, EC 6, ligases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.
EC 6.1: Forming Carbon-Oxygen Bonds
EC 6.1.1: Ligases Forming Aminoacyl-tRNA and Related Compounds (Aminoacyl tRNA synthetase)
- EC 6.1.1.1: tyrosine-tRNA ligase
- EC 6.1.1.2: tryptophan-tRNA ligase
- EC 6.1.1.3: threonine-tRNA ligase
- EC 6.1.1.4: leucine-tRNA ligase
- EC 6.1.1.5: isoleucine-tRNA ligase
- EC 6.1.1.6: lysine-tRNA ligase
- EC 6.1.1.7: alanine-tRNA ligase
- EC 6.1.1.8: Deleted
- EC 6.1.1.9: valine-tRNA ligase
- EC 6.1.1.10: methionine-tRNA ligase
- EC 6.1.1.11: serine-tRNA ligase
- EC 6.1.1.12: aspartate-tRNA ligase
- EC 6.1.1.13: D-alanine-poly(phosphoribitol) ligase
- EC 6.1.1.14: glycine-tRNA ligase
- EC 6.1.1.15: proline-tRNA ligase
- EC 6.1.1.16: cysteine-tRNA ligase
- EC 6.1.1.17: glutamate-tRNA ligase
- EC 6.1.1.18: glutamine-tRNA ligase
- EC 6.1.1.19: arginine-tRNA ligase
- EC 6.1.1.20: phenylalanine-tRNA ligase
- EC 6.1.1.21: histidine-tRNA ligase
- EC 6.1.1.22: asparagine-tRNA ligase
- EC 6.1.1.23: aspartate-tRNAAsn ligase
- EC 6.1.1.24: glutamate-tRNAGln ligase
- EC 6.1.1.25: lysine-tRNAPyl ligase
EC 6.2: Forming Carbon-Sulfur Bonds
EC 6.2.1: Acid-Thiol Ligases
- EC 6.2.1.1: acetate-CoA ligase
- EC 6.2.1.2: butyrate-CoA ligase
- EC 6.2.1.3: long-chain-fatty-acid-CoA ligase
- EC 6.2.1.4: succinate-CoA ligase (GDP-forming)
- EC 6.2.1.5: succinate-CoA ligase (ADP-forming)
- EC 6.2.1.6: glutarate-CoA ligase
- EC 6.2.1.7: cholate-CoA ligase
- EC 6.2.1.8: oxalate-CoA ligase
- EC 6.2.1.9: malate-CoA ligase
- EC 6.2.1.10: acid-CoA ligase (GDP-forming)
- EC 6.2.1.11: biotin-CoA ligase
- EC 6.2.1.12: 4-coumarate-CoA ligase
- EC 6.2.1.13: acetate-CoA ligase (ADP-forming)
- EC 6.2.1.14: 6-carboxyhexanoate-CoA ligase
- EC 6.2.1.15: arachidonate-CoA ligase
- EC 6.2.1.16: acetoacetate-CoA ligase
- EC 6.2.1.17: propionate-CoA ligase
- EC 6.2.1.18: citrate-CoA ligase
- EC 6.2.1.19: long-chain-fatty-acid-luciferin-component ligase
- EC 6.2.1.20: long-chain-fatty-acid-(acyl-carrier-protein) ligase
- EC 6.2.1.21: Covered by EC 6.2.1.30
- EC 6.2.1.22: (citrate (pro-3S)-lyase) ligase
- EC 6.2.1.23: dicarboxylate-CoA ligase
- EC 6.2.1.24: phytanate-CoA ligase
- EC 6.2.1.25: benzoate-CoA ligase
- EC 6.2.1.26: o-succinylbenzoate-CoA ligase
- EC 6.2.1.27: 4-hydroxybenzoate-CoA ligase
- EC 6.2.1.28: 3a,7a-dihydroxy-5b-cholestanate-CoA ligase
- EC 6.2.1.29: Deleted, now EC 6.2.1.7
- EC 6.2.1.30: phenylacetate-CoA ligase
- EC 6.2.1.31: 2-furoate-CoA ligase
- EC 6.2.1.32: anthranilate-CoA ligase
- EC 6.2.1.33: 4-chlorobenzoate-CoA ligase
- EC 6.2.1.34: trans-feruloyl-CoA synthase
EC 6.3: Forming Carbon-Nitrogen Bonds
EC 6.3.1: Acid-Ammonia (or Amine) Ligases (Amide Synthases)
- EC 6.3.1.1: aspartate-ammonia ligase
- EC 6.3.1.2: glutamate-ammonia ligase
- EC 6.3.1.3: Now EC 6.3.4.13
- EC 6.3.1.4: aspartate-ammonia ligase (ADP-forming)
- EC 6.3.1.5: NAD+ synthase
- EC 6.3.1.6: glutamate-ethylamine ligase
- EC 6.3.1.7: 4-methyleneglutamate-ammonia ligase
- EC 6.3.1.8: glutathionylspermidine synthase
- EC 6.3.1.9: trypanothione synthase
- EC 6.3.1.10: adenosylcobinamide-phosphate synthase
- EC 6.3.1.11: glutamate-putrescine ligase
EC 6.3.2: Acid-Amino-Acid Ligases (Peptide Synthases)
- EC 6.3.2.1: pantoate-b-alanine ligase
- EC 6.3.2.2: glutamate-cysteine ligase
- EC 6.3.2.3: glutathione synthase
- EC 6.3.2.4: D-alanine-D-alanine ligase
- EC 6.3.2.5: phosphopantothenate-cysteine ligase
- EC 6.3.2.6: phosphoribosylaminoimidazolesuccinocarboxamide synthase
- EC 6.3.2.7: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase
- EC 6.3.2.8: UDP-N-acetylmuramate-L-alanine ligase
- EC 6.3.2.9: UDP-N-acetylmuramoylalanine-D-glutamate ligase
- EC 6.3.2.10: UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase
- EC 6.3.2.11: carnosine synthase
- EC 6.3.2.12: dihydrofolate synthase
- EC 6.3.2.13: UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diamino-pimelate ligase
- EC 6.3.2.14: 2,3-dihydroxybenzoate-serine ligase
- EC 6.3.2.15: Deleted, due to EC 6.3.2.10
- EC 6.3.2.16: D-alanine-alanyl-poly(glycerolphosphate) ligase
- EC 6.3.2.17: tetrahydrofolate synthase
- EC 6.3.2.18: g-glutamylhistamine synthase
- EC 6.3.2.19: ubiquitin-protein ligase
- EC 6.3.2.20: indoleacetate-lysine synthetase
- EC 6.3.2.21: ubiquitin-calmodulin ligase
- EC 6.3.2.22: diphthine-ammonia ligase
- EC 6.3.2.23: homoglutathione synthase
- EC 6.3.2.24: tyrosine-arginine ligase
- EC 6.3.2.25: tubulin-tyrosine ligase
- EC 6.3.2.26: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
- EC 6.3.2.27: aerobactin synthase
EC 6.3.3: Cyclo-Ligases
- EC 6.3.3.1: phosphoribosylformylglycinamidine cyclo-ligase
- EC 6.3.3.2: 5-formyltetrahydrofolate cyclo-ligase
- EC 6.3.3.3: dethiobiotin synthase
- EC 6.3.3.4: (carboxyethyl)arginine b-lactam-synthase
EC 6.3.4: Other Carbon-Nitrogen Ligases
- EC 6.3.4.1: GMP synthase
- EC 6.3.4.2: CTP synthase
- EC 6.3.4.3: formate-tetrahydrofolate ligase
- EC 6.3.4.4: adenylosuccinate synthase
- EC 6.3.4.5: argininosuccinate synthase
- EC 6.3.4.6: urea carboxylase
- EC 6.3.4.7: ribose-5-phosphate-ammonia ligase
- EC 6.3.4.8: imidazoleacetate-phosphoribosyldiphosphate ligase
- EC 6.3.4.9: biotin-(methylmalonyl-CoA-carboxytransferase) ligase
- EC 6.3.4.10: biotin-(propionyl-CoA-carboxylase (ATP-hydrolysing)) ligase
- EC 6.3.4.11: biotin-(methylcrotonoyl-CoA-carboxylase) ligase
- EC 6.3.4.12: glutamate-methylamine ligase
- EC 6.3.4.13: phosphoribosylamine-glycine ligase
- EC 6.3.4.14: biotin carboxylase
- EC 6.3.4.15: biotin-(acetyl-CoA-carboxylase) ligase
- EC 6.3.4.16: carbamoyl-phosphate synthase (ammonia)
- EC 6.3.4.17: formate-dihydrofolate ligase
EC 6.3.5: Carbon-Nitrogen Ligases with Glutamine as Amido-N-Donor
- EC 6.3.5.1: NAD+ synthase (glutamine-hydrolysing)
- EC 6.3.5.2: GMP synthase (glutamine-hydrolysing)
- EC 6.3.5.3: phosphoribosylformylglycinamidine synthase
- EC 6.3.5.4: asparagine synthase (glutamine-hydrolysing)
- EC 6.3.5.5: carbamoyl-phosphate synthase (glutamine-hydrolysing)
- EC 6.3.5.6: asparaginyl-tRNA synthase (glutamine-hydrolysing)
- EC 6.3.5.7: glutaminyl-tRNA synthase (glutamine-hydrolysing)
- EC 6.3.5.8: aminodeoxychorismate synthase
- EC 6.3.5.9: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)
- EC 6.3.5.10: adenosylcobyric acid synthase (glutamine-hydrolysing)
EC 6.4: Forming Carbon-Carbon Bonds
- EC 6.4.1.1: pyruvate carboxylase
- EC 6.4.1.2: acetyl-CoA carboxylase
- EC 6.4.1.3: propionyl-CoA carboxylase
- EC 6.4.1.4: methylcrotonoyl-CoA carboxylase
- EC 6.4.1.5: geranoyl-CoA carboxylase
- EC 6.4.1.6: acetone carboxylase
EC 6.5: Forming Phosphoric Ester Bonds
- EC 6.5.1.1: DNA ligase (ATP)
- EC 6.5.1.2: DNA ligase (NAD+)
- EC 6.5.1.3: RNA ligase (ATP)
- EC 6.5.1.4: RNA-3'-phosphate cyclase
EC 6.6: Forming Nitrogen-Metal Bonds
EC 6.6.1: Forming Coordination Complexes
Proteins: enzymes | |
|---|---|
| Topics | Active site - Allosteric regulation - Binding site - Catalytically perfect enzyme - Coenzyme - Cofactor - Cooperativity - EC number Enzyme catalysis - Enzyme inhibitor - Enzyme kinetics - Lineweaver-Burk plot - Michaelis-Menten kinetics - List of enzymes |
| Types | EC1 Oxidoreductases/list - EC2 Transferases/list - EC3 Hydrolases/list - EC4 Lyases/list - EC5 Isomerases/list - EC6 Ligases/list |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

