Livedoid vasculitis
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| Livedoid vasculitis Classification and external resources | |
| ICD-10 | L95.0 |
|---|---|
| ICD-9 | xxx |
| DiseasesDB | 7546 |
| MedlinePlus | 001478 |
| eMedicine | derm/39 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
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Overview
Livedoid vasculitis (also known as "livedo vasculitis", "livedo reticularis", and "livedoid vasculopathy") is a vascular disorder mostly affecting women. It may be aggravated by exposure to cold and occurs most often in the lower extremities. It can also be associated with the presence of anti-cardiolipin antibodies (the Antiphospholipid syndrome).
The condition's name derives from the Latin livere meaning bluish.
Etiology
A number of conditions may cause the appearance of livedo reticularis:
- Cutis marmorata telangiectatica congenita a rare congenital condition
- Sneddon syndrome - association of Livedoid vasculitis and systemic vascular disorders, such as strokes, due to underlying genetic cause.[1]
- Idiopathic livedo reticularis - is the commonest cause of livedo reticularis appearance and is a completely benign condition of unknown cause affecting mostly young women during the winter.[1] May be mild, but ulceration may occur later in the summer.[1]
- Secondary livedo reticularis:
- Vasculitis autoimmune conditions:
- Livedoid vasculitis - with painful ulceration occurring in the lower legs
- Polyarteritis nodosa
- Systemic lupus erythematosus[1]
- Dermatomyositis
- Rheumatoid arthritis
- Lymphoma
- Pancreatitis[1]
- Tuberculosis
- Amantadine (drug)
- Obstruction of capillaries:
- Cryoglobulinaemia - proteins in the blood that clump together in cold conditions.[1]
- Antiphospholipid syndrome due to small blood clots
- Hypercalcaemia (raised blood calcium levels which may be deposited in the capillaries)
- Haematological disorders of Polycythaemia rubra vera or Thrombocytosis (excessive red cells or platelets)
- Infections (syphilis and tuberculosis)
- Arteriosclerosis (cholesterol emboli syndrome)[1][1] and homocystinuria (due to Chromosome 21 autosomal recessive Cystathionine beta synthase deficiency)
- Intra-arterial injection (especially in drug addicts)
- Vasculitis autoimmune conditions:
Treatment
Other than identifying and treating any underlying conditions in secondary livedo,[1] idiopathic livedo reticularis itself may improve with warming the legs, but once established the skin discolouration may become permanent.
Footnotes
External links
WikiDoc Research Resources for Livedoid vasculitis | |
|---|---|
| Articles on Livedoid vasculitis | Most recent articles on Livedoid vasculitis • Most cited articles on Livedoid vasculitis • Review articles on Livedoid vasculitis • Articles on Livedoid vasculitis in N Eng J Med, Lancet, BMJ |
| Media (Slides, Video, Images, MP3) on Livedoid vasculitis | Powerpoint slides on Livedoid vasculitis • Images of Livedoid vasculitis • Photos of Livedoid vasculitis • Podcasts & MP3s on Livedoid vasculitis • Videos on Livedoid vasculitis |
| Evidence Based Medicine Regarding Livedoid vasculitis | Cochrane Collaboration on Livedoid vasculitis • Bandolier on Livedoid vasculitis • TRIP on Livedoid vasculitis |
| Cost Effectiveness of Livedoid vasculitis | Cost Effectiveness of Livedoid vasculitis |
| Clinical Trials Involving Livedoid vasculitis | Ongoing Trials on Livedoid vasculitis at Clinical Trials.gov • Trial results on Livedoid vasculitis • Clinical Trials on Livedoid vasculitis at Google |
| Guidelines / Policies / Government Resources (FDA/CDC) Regarding Livedoid vasculitis | US National Guidelines Clearinghouse on Livedoid vasculitis • NICE Guidance on Livedoid vasculitis • NHS PRODIGY Guidance • FDA on Livedoid vasculitis • CDC on Livedoid vasculitis |
| Textbook Information on Livedoid vasculitis | Books and Textbook Information on Livedoid vasculitis |
| Pharmacology Resources on Livedoid vasculitis | Dosing of Livedoid vasculitis • Drug interactions with Livedoid vasculitis • Side effects of Livedoid vasculitis • Allergic reactions to Livedoid vasculitis • Overdose information on Livedoid vasculitis • Carcinogenicity information on Livedoid vasculitis • Livedoid vasculitis in pregnancy • Pharmacokinetics of Livedoid vasculitis • |
| Genetics, Pharmacogenomics, and Proteinomics of Livedoid vasculitis | Genetics of Livedoid vasculitis • Pharmacogenomics of Livedoid vasculitis • Proteomics of Livedoid vasculitis |
| Newstories on Livedoid vasculitis | Livedoid vasculitis in the news • Be alerted to news on Livedoid vasculitis • News trends on Livedoid vasculitis |
| Commentary on Livedoid vasculitis | Blogs on Livedoid vasculitis |
| Patient Resources on Livedoid vasculitis | Patient resources on Livedoid vasculitis • Discussion groups on Livedoid vasculitis • Patient Handouts on Livedoid vasculitis • Directions to Hospitals Treating Livedoid vasculitis • Risk calculators and risk factors for Livedoid vasculitis |
| Healthcare Provider Resources on Livedoid vasculitis | Symptoms of Livedoid vasculitis • Causes & Risk Factors for Livedoid vasculitis • Diagnostic studies for Livedoid vasculitis • Treatment of Livedoid vasculitis |
| Continuing Medical Education (CME) Programs on Livedoid vasculitis | CME Programs on Livedoid vasculitis |
| International Resources on Livedoid vasculitis | Livedoid vasculitis en Espanol • Livedoid vasculitis en Francais |
| Business Resources on Livedoid vasculitis | Livedoid vasculitis in the Marketplace • Patents on Livedoid vasculitis |
| Informatics Resources on Livedoid vasculitis | List of terms related to Livedoid vasculitis |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
