Lucey-Driscoll syndrome

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Lucey-Driscoll syndrome is a cause of transient familial neonatal unconjugated hyperbilirubinemia. It may be caused by maternal steroids passed on through breast milk to the newborn. It is different from breast milk jaundice (breast-fed infants have higher bilirubine levels than formula-fed ones).

Children may also be heterozygous in the UGT1A1-gene, also linked to Crigler-Najjar syndrome and Gilbert's syndrome.

References

• Online 'Mendelian Inheritance in Man' (OMIM) 237900 - transient familial neonatal hyperbilirubinemia, breast feeding jaundice included]
• med/1066 at eMedicine - Unconjugated hyperbilirubinemia