Luciferin

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Image:Firefly-luciferin-3D-vdW.png
This is a space-filling model of firefly luciferin. Color coding: yellow=sulfur; blue=nitrogen; black=carbon; red=oxygen; white=hydrogen.

Luciferins (from the Latin lucifer, "light-bringing" [1]) are a class of light-emitting biological pigments found in organisms capable of bioluminescence.

Contents

Types of luciferin

Luciferins are a class of small-molecule substrate each for their corresponding protein enzyme luciferase. Luciferins are oxidized in the presence of the enzyme luciferase to produce oxyluciferin and energy in the form of light. There are five general types of luciferins.

Image:Firefly-luciferin-2D-skeletal.png
This structure of firefly luciferin is reversed (left to right) from the space-filling model shown above

Firefly luciferin

Firefly luciferin is the luciferin found in fireflies. It is the substrate of luciferase (EC 1.13.12.7) Johns Hopkins University synthesized luciferin, the substance which lights the tail of the firefly, furthering research on ATP, the primary energy source in biological action (1962).

Bacterial luciferin

Bacterial luciferin is a type of luciferin found in bacteria, some squid and fish. It consists of a long-chain aldehyde and a reduced riboflavin phosphate.

Dinoflagellate luciferin

Dinoflagellate luciferin is a chlorophyll derivative and is found in dinoflagellates, which are often responsible for the phenomenon of nighttime ocean phosphorescence. A very similar type of luciferin is found in some types of euphausiid shrimp.

Vargulin

Vargulin is found in certain deep-sea fish; specifically, ostracods and Poricthys. It is an imidazolopyrazine.

Coelenterazine

Coelenterazine is found in radiolarians, ctenophores, cnidarians, squid, copepods, chaetognaths, fish and shrimp. It is the light-emitting molecule in the protein aequorin.

External links

eo:Luciferino fr:Luciférine nl:Luciferine ja:ルシフェリン


Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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