First pharyngeal arch

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First branchial arch
Diagram showing the regions of the adult face and neck related to the fronto-nasal process and the branchial arches.
Under surface of the head of a human embryo about twenty-nine days old.
Gray's	subject #13 66
MeSH	Branchial+Region
Dorlands/Elsevier	a_57/12149860

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Overview

The first branchial arch, also called the first pharyngeal arch and mandibular arch, is the first of six branchial arches that develops in fetal life. It is located between the stomodeum and the first pharyngeal groove.

Processes

This arch divides into a maxillary process and a mandibular process, giving rise to structures including the bones of the lower two-thirds of the face and the jaw. The maxillary process becomes the maxilla (or upper jaw), and palate while the mandibular process becomes the lower jaw. This arch also gives rise to the muscles of mastication.

Innervation of the two processes of the first branchial arch is provided by two distinct branches of the trigeminal nerve (CN V),^[1] the mandibular and maxillary branches. The artery of the first arch is the first aortic arch,^[1] which partially persists as the maxillary artery.

Meckel's cartilage

Meckel's cartilage forms in the mesoderm of the mandibular process and eventually regresses to form the incus and malleus of the middle ear; the anterior ligament of the malleus and the sphenomandibular ligament. The mandible or lower jaw forms by intramembranous ossification using Meckel's cartilage as a 'template', but the mandible does not arise from direct ossification of Meckel's cartilage.

Derivatives of the first arch

Derivatives of the first arch:

• Ectodermal and endodermal
  • mucous membrane and glands of the anterior two thirds of the tongue
• Mesodermal
  • muscles of mastication (chewing)
    • masseter
    • pterygoid muscles
    • temporalis muscles
  • mylohyoid muscle
  • digastric muscle, anterior belly
  • tensor palati muscle
  • tensor tympani muscle

Additional images

Human embryo from thirty-one to thirty-four days.	Head end of human embryo, about the end of the fourth week.	Floor of pharynx of embryo between 18 and 21 days.	Head end of human embryo of about thirty to thirty-one days.
The head and neck of a human embryo thirty-two days old, seen from the ventral surface.

References

External links

• Embryology at UNC hednk-011
• Overview at University of Newcastle
• Overview at Howard University

v • d • e Human development of head and neck
Branchial region	Pharyngeal arch (1st, 2nd) - Pharyngeal pouch - Pharyngeal groove - Cervical sinus Frontonasal prominence - Maxillary prominence - Mandibular prominence (Meckel's cartilage) tongue: Lateral lingual swelling - Tuberculum impar nose: Nasal placode - Olfactory pit - nasal prominences (Lateral, Medial) - Intermaxillary segment palate: Primitive palate - Secondary palate
Tooth development	Dental papilla - Odontoblast - Ameloblast - Hertwig's epithelial root sheath - Epithelial cell rests of Malassez - Cementoblast
Thyroid	Thyroid diverticulum - Thyroglossal duct - Ultimobranchial body

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .