Marasmus

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Overview

Marasmus
Classification and external resources
ICD-10 E41.-E42.
ICD-9 261
DiseasesDB 7826
eMedicine ped/164 
MeSH D011502

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Marasmus

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Marasmus is a form of severe protein-energy malnutrition characterised by energy deficiency. Some other PEMs are kwashiorkor and cachexia (the most common one in the developed world).

A child with marasmus looks emaciated and the body weight may reduce to less than 80% of the normal weight for that height.

Marasmus occurrence increases prior to age 1 whereas Kwashiorkor occurrence increases after 18 months.

Signs

The signs of common characteristics of protein-energy malnutrition: dry skin, loose skin folds hanging over the glutei, axillae, etc. Drastic loss of adipose tissue from normal areas of fat deposits like buttocks and thighs. The afflicted are often fretful, irritable, and voraciously hungry. There may be alternate bands of pigmented and depigmented hair (flag sign), or flaky paint appearance of skin due to peeling.

Treatment

It is essential to treat not only the symptoms but also the complications of the disorder like infections, dehydration and circulation disorders, which are frequently lethal and lead to high mortality if ignored.

Ultimately marasmus progresses to the point of no return when the body's machinery for protein synthesis, itself made of protein, has been degraded. At this point, attempts to correct the situation by giving food or protein fail to prevent death.

Causes

Marasmus is caused by failure to take in sufficient calories.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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