Marburg multiple sclerosis
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Marburg multiple sclerosis, also known as malignant, acute or fulminant multiple sclerosis, is considered one of the multiple sclerosis borderline diseases, which is a collection of diseases classified by some as MS variants and by others as different diseases. Other diseases in this group are Neuromyelitis optica (NMO), Balo concentric sclerosis and Schilder's disease.[1]
It took its name from Otto Marburg. It can be diagnosed in vivo with an MRI.[1]
It is usually lethal, but recently it has been found to be responsive to Mitoxantrone[1] and Alemtuzumab,[1] and it has also been responsive to autologous stem cells transplantation.[1]
See also
External links
References
Multiple sclerosis | |
|---|---|
| Signs and symptoms | Ataxia · Depression · Diplopia · Dysarthria · Dysphagia · Fatigue · Incontinence · Neurological fatigue · Nystagmus · Optic neuritis · Pain · Uhthoff's phenomenon |
| Diagnosis and evolution following | McDonald criteria · EDSS |
| Investigation | Pathophysiology · Experimental autoimmune encephalomyelitis |
| Treatment | Interferon · Glatiramer acetate · Mitoxantrone · Natalizumab · Therapies under investigation |
| Borderline forms | Acute disseminated encephalomyelitis · Balo concentric sclerosis · Devic's disease · Guillain-Barré syndrome · Marburg multiple sclerosis · Schilder's disease |
| Other | List of people with multiple sclerosis · List of multiple sclerosis organizations |
 | This disease article is a stub. You can help WikiDoc by expanding it. |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
