May Hegglin anomaly

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May Hegglin anomaly
Classification and external resources
ICD-10 D72.0
ICD-9 288.2
OMIM 155100
DiseasesDB 29517
eMedicine ped/1383 

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May Hegglin's anomaly, as it is also known, is a rare genetic disorder of the blood platelets that causes them to be abnormally large. Also, this anomaly causes abnormalities in the white blood cells known as leukocytes.

Presentation

In the leukocytes, the presence of very small rods (around 3 micrometers), or Dohle bodies can be seen in the cytoplasm.

Treatment

In many cases, May Hegglin's requires no treatment. However, in extreme cases, blood platelet transfusions may be necessary

Causes

An association with MYH9 has been described.[1]

References

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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