Meckel's diverticulum
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Overview
| Meckel's diverticulum Classification and external resources | |
 | |
|---|---|
| Meckel's diverticulum | |
| ICD-10 | C17.3, Q43.0 |
| ICD-9 | 152.3, 751.0 |
| OMIM | 155140 |
| DiseasesDB | 7903 |
| eMedicine | med/2797 ped/1389 rad/425 |
| MeSH | D008467 |
A Meckel's diverticulum, a true congenital diverticulum, is a small bulge in the small intestine present at birth. It is a vestigial remnant of the omphalomesenteric duct (also called the vitelline duct), and is the most frequent malformation of the gastrointestinal tract. It is present in approximately 2% of the population, with males more frequently experiencing symptoms.
It is named after Johann Friedrich Meckel, who first described this type of diverticulum in 1809.[1][1]
Presentation
Meckel's diverticulum is located in the distal ileum, usually within about 60-100 cm of the ileocecal valve. It is typically 3-5 cm long, runs antimesenterically and has its own blood supply. It's left over from the umbilical cord and intestines from our embryonic life.
A memory aid is the rule of 2's: 2% (of the population) - 2 feet (from the ileocecal valve) - 2 inches (in length) - 2% are symptomatic, there are 2 types of common ectopic tissue (gastric and pancreatic), the most common age at clinical presentation is 2, and males are 2 times as likely to be affected.
It can also be present as an indirect hernia, where it is known as a "Hernia of Littre." Furthermore, it can be attached to the umbilical region by the vitelline ligament, with the possibility of vitelline cysts, or even a patent vitelline canal forming a vitelline fistula when the umbilical cord is cut. Torsions of intestine around the intestinal stalk may also occur, leading to obstruction, ischemia, and necrosis.
Symptoms
Approximately 98% of people afflicted with Meckel's diverticulum are asymptomatic. If symptoms do occur, they typically appear before the age of two.
The most common presenting symptom is painless rectal bleeding, followed by intestinal obstruction, volvulus and intussusception. Occasionally, Meckel's diverticulitis may present with all the features of acute appendicitis. Also, severe pain in the upper abdomen is experienced by the patient along with bloating of the stomach region. At times, the symptoms are so painful such that they may cause sleepless nights with extreme pain in the abdominal area.
Diagnosis
A technetium-99m (99mTc) pertechnetate scan is the investigation of choice to diagnose Meckel's diverticula. This scan detects gastric mucosa; since approximately 50% of symptomatic Meckel's diverticula have ectopic gastric (stomach) cells contained within them, this is displayed as a spot on the scan distant from the stomach itself. Patients with these misplaced gastric cells may experience peptic ulcers as a consequence. Other tests such as colonoscopy and screenings for bleeding disorders should be performed, and angiography can assist in determining the location and severity of bleeding.
Treatment
Treatment is surgical, consisting of a resection of the affected portion of the bowel.
References
Congenital malformations and deformations of digestive system (Q35-Q45, 749-751) | |
|---|---|
| Tongue, mouth and pharynx | Cleft lip and palate - Van der Woude syndrome - Ankyloglossia - Macroglossia - Pharyngeal pouch |
| Esophagus and upper alimentary tract | Esophageal atresia - Tracheoesophageal fistula - Esophageal web - Pyloric stenosis - Hiatus hernia |
| Intestines | Intestinal atresia (Duodenal atresia) - Imperforate anus - Meckel's diverticulum - Hirschsprung's disease - Intestinal malrotation - Persistent cloaca |
| Pancreas | Annular pancreas - Accessory pancreas - Pancreas divisum |
| Other | Choledochal cysts - Alagille syndrome |
| See also non-congenital (K20-K93, 530-579) | |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
