Melanocytic tumors of uncertain malignant potential

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Melanocytic tumors of uncertain malignant potential (MELTUMP) are melanocytic lesions in the dermis that cannot be classified by morphology as either benign naevi (moles) or malignant melanomas because the mass shows features of both.

Several lesion types may be classified as MELTUMPs: atypical Spitz naevi, dysplastic naevi, pigmented epithelioid melanocytoma, deep penetrating naevi, congenital neavi, cellular nodules in congenital naevi, possible naevoid melanomas, and cellular blue naevi.^[1][1]

A related category of melanocytic proliferation is superficial atypical melanocytic proliferations of uncertain significance (SAMPUS), which includes junctional melanocytic proliferations and proliferations in the epidermis and papillary dermis that are not accompanied by tumorigenic cell mitosis.^[1]

References

Further readings

• Murphy, George F. "Case 12: Melanocytic tumor of uncertain malignant potential (MELTUMP)", in Artur Zembowicz (ed): Cases in Dermatopathology: Common Problems in Diagnosis of Pigmented Lesions. Los Gatos, California: Knowledge Books and Software, 73–80. ISBN 1741620880. 

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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .