Mequitazine
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| Image:Mequitazine.svg | |
| Mequitazine
| |
| Systematic (IUPAC) name | |
| 10-(4-azabicyclo[2.2.2] oct-7-ylmethyl) phenothiazine | |
| Identifiers | |
| CAS number | |
| ATC code | R06 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C20H22N2S |
| Mol. mass | 322.468 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Mequitazine is an antihistamine.
External links
- Ramírez Chanona N, del Rio Navarro B, Pérez Martín J. "Efficacy of mequitazine (Primalan) on the relief of symptoms of allergic rhinoconjunctivitis in children. Documented clinical experience". Rev Alerg Mex 52 (6): 221-5. PMID 16568706.
- Theunissen E, Vermeeren A, van Oers A, van Maris I, Ramaekers J (2004). "A dose-ranging study of the effects of mequitazine on actual driving, memory and psychomotor performance as compared to dexchlorpheniramine, cetirizine and placebo.". Clin Exp Allergy 34 (2): 250-8. PMID 14987305.
- Nakamura K, Yokoi T, Kodama T, Inoue K, Nagashima K, Shimada N, Shimizu T, Kamataki T (1998). "Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes.". J Pharmacol Exp Ther 284 (2): 437-42. PMID 9454781.
- Persi L, Dupin O, Arnaud B, Trinquand C, Michel F, Bousquet J (1997). "Efficacy of mequitazine in comparison with placebo assessed by ocular challenge with allergen in allergic conjunctivitis.". Allergy 52 (4): 451-4. PMID 9188930.
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
