Methylmalonyl-CoA

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Methylmalonyl-CoA
Image:Methylmalonyl-CoA.PNG
Identifiers
CAS number 1264-45-5
PubChem 123909
MeSH methylmalonyl-coenzyme+A
Properties
Molecular formula C25H40N7O19P3S
Molar mass 867.608 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Methylmalonyl-CoA is the coenzyme A linked form of methylmalonic acid.

It is formed from Propionyl-CoA by Propionyl-CoA carboxylase.

It is converted into Succinyl-CoA by Methylmalonyl-CoA mutase, in a reaction that requires Vitamin B12 as a cofactor. In this way, it enters the Krebs cycle, and is thus part of one of the anaplerotic reactions.

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