Muscle type nicotinic receptor

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The muscle type nicotinic receptor is a type of nicotinic acetylcholine receptor, consisting of the subunit combination (α1)₂β1δε^[1].

It is located in the neuromuscular junction, where activation yields EPSP, mainly by increased Na⁺ and K⁺ permeability.

Agonists

Nicotinic agonists for this receptor include:

• acetylcholine
• carbachol
• suxamethonium

Antagonists

• α-bungarotoxin ^[1]
• α-conotoxin
• tubocurarine
• pancuronium
• hexamethonium

References

v • d • e Ion channel, receptor: ligand-gated ion channels
Cys-loop receptors	5-HT receptor (5-HT3 serotonin receptor (A)) - GABA receptor (GABA A (α1, α2, α3, α5, α6, β1, β2, β3, γ2, ε), GABA C (ρ1)) - Glycine receptor (α1) - Nicotinic acetylcholine receptor (α1, α2, α3, α4, α5, α7, β2, β3, β4, δ, ε, (α4)2(β2)3, (α7)5, Ganglion type, Muscle type)
Ionotropic glutamate receptors	AMPA (1, 2, 3, 4) - Kainate (1, 2) - NMDA (1, 2A, 2B, 2C, 2D)
ATP-gated channels	Purinergic receptors (P2X (1, 4, 5, 7))