Mycobacterium brisbanense
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
| Mycobacterium brisbanense | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Scientific classification | ||||||||||||||
| ||||||||||||||
| Binomial name | ||||||||||||||
| Mycobacterium brisbanense Schinsky et al. 2004, ATCC 49938 |
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Mycobacterium brisbanense is a member of the Mycobacterium fortuitum third biovariant complex. They are rapidly growing ubiquitous environmental organisms that normally inhabit soil, dust and water. These organisms frequently are human pathogens that cause a wide spectrum of clinically significant disease. It is important for practitioners to be aware of these organisms as possible etiological agents, as they are resistant to most first-line anti-tuberculous agents.
- Etymology: brisbanense, pertaining to Brisbane, Queensland, Australia, the source of the type strain.
Description
Microscopy
- The organisms are acid-fast, Gram-positive, pleomorphic bacilli. Long filamentous forms are often observed, but spores and capsules are absent.
Colony characteristics
- Colonies are mucoid, convex, round, entire-edged and do not demonstrate aerial hyphae.
- Colonies are white to slightly beige and small in diameter (approx. 1 mm) after incubation on heart infusion agar with 5 % (v/v) rabbit blood for 2 days at 35 °C.
Physiology
- Growth occurs on Löwenstein–Jensen medium at 35 °C in less than 7 days, but no growth occurs at 42 °C.
- Growth occurs on 5 % NaCl and on MacConkey's agar without crystal violet at 28 °C.
- Arylsulfatase activity by 3 days, utilizes acetamide, reduces nitrate, produces urease and exhibits iron uptake.
- It does not utilize citrate or grow in lysozyme. Semi-quantitative catalase activity is weakly positive (<45 mm).
- It does not utilize citrate, grow in lysozyme or produce thermostable catalase.
Differential characteristics
- The nearest phylogenetic neighbour, according to 16S rRNA gene sequence similarity, is Mycobacterium diernhoferi ATCC 19340T.
Pathogenesis
- Reported infections include skin and soft-tissue abscesses with associated osteomyelitis, bacteraemia, endocarditis, keratitis, lymphadenitis, peritonitis, post-surgical infections, pulmonary infections and disseminated disease. Involvement of the central nervous system is rare, but meningitis may develop after trauma or surgery. The immunocompromised patient is at special risk for developing severe diseases, especially catheter-related infection with bacteraemia.
Type Strain
- First isolated from an antral sinus in Brisbane, Queensland, Australia
- Strain W6743 = ATCC 49938 = CCUG 47584 = DSM 44680
References
- Schinsky M.F., 2004. Taxonomic variation in the Mycobacterium fortuitum third biovariant complex: description of Mycobacterium boenickei sp. nov., Mycobacterium houstonense sp. nov., Mycobacterium neworleansense sp. nov. and Mycobacterium brisbanense sp. nov. and recognition of Mycobacterium porcinum from human clinical isolates. Int. J. Syst. Evol. Microbiol., 2004, 54, 1653-1667.
de:Mycobacterium brisbanense nl:Mycobacterium brisbanense
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
