Iohexol
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| Image:Iohexol.svg | |
| Iohexol
| |
| Systematic (IUPAC) name | |
| 5-(acetyl-(2,3-dihydroxypropyl)amino)-N,N'-bis (2,3-dihydroxypropyl)-2,4,6-triiodo-benzene-1,3- dicarboxamide | |
| Identifiers | |
| CAS number | |
| ATC code | V08 |
| PubChem | |
| Chemical data | |
| Formula | C19H26I3N3O9 |
| Mol. mass | 821.138 g/mol |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | Low |
| Metabolism | Nil |
| Half life | Variable |
| Excretion | Renal, unchanged |
| Therapeutic considerations | |
| Pregnancy cat. |
B(US) |
| Legal status |
℞ Prescription only |
| Routes | Intrathecal, intravascular, oral, intracavital |
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Overview
Iohexol is a contrast agent, sold under the trade name Omnipaque. It is available in various concentrations, from 140 to 350 milligrams of iodine per milliliter. Omnipaque 350 is commonly used as a contrast agent during coronary angiography.
The osmolality of iohexol ranges from 322 mOsm/kg—approximately 1.1 times that of blood plasma—to 844 mOsm/kg, almost three times that of blood.[1] Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate, may be more than twice as high.[1]
References
External links
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
