Neural tube defects
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| It has been suggested that this article or section be merged with Neural tube defect. (Discuss) |
| Neural tube defects Classification and external resources | |
| OMIM | 182940 |
|---|---|
| DiseasesDB | 8926 |
| eMedicine | neuro/244 ped/2805 |
| MeSH | D009436 |
Normally, in human embryos, the closure of the neural tube occurs around the 30th day after fertilization. However, if something interferes and the tube fails to close properly, a neural tube defect will occur.
The incidence of neural tube defects is 2.6 in 1,000 worldwide. [citation needed]
Causes
Pregnant women taking medication for epilepsy have a higher chance of having a child with a neural tube defect. Research has shown that women with folic acid deficiencies also have a higher chance of having a child with a neural tube defect, but this is only one factor. Taking folic acid does not completely negate the risk of neural tube problems, but it does significantly reduce the risk.
Prevention
In Canada, mandatory fortification of selected foods with folic acid has been shown to reduce the incidence of neural tube defects by 46%[1].
Women who are or could become pregnant are advised to take daily supplements of folic acid, unless their dietary intake of this nutrient is normally high.
Detection
Neural tube defects may be detected by a variety of methods, including some prenatal screening tests and medical imaging. Often, these defects are apparent at birth, but occult defects may be not diagnosed until much later in life.
Types of neural tube defects
- Anencephaly
- Encephalocele
- Spina bifida including myelomeningocele and others
References
See also
External links
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he:פגמים בתעלה העיצבית nl:Neuraalbuisdefect
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
