OR2AE1
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| Olfactory receptor, family 2, subfamily AE, member 1
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| Identifiers | ||||||||||||||
| Symbol(s) | OR2AE1; OR2AE2 | |||||||||||||
| External IDs | MGI: 3030004 Homologene: 79678 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 81392 | 258959 | ||||||||||||
| Ensembl | ENSG00000176607 | ENSMUSG00000062245 | ||||||||||||
| Uniprot | Q8NHA4 | na | ||||||||||||
| Refseq | NM_001005276 (mRNA) NP_001005276 (protein) | NM_146957 (mRNA) NP_667168 (protein) | ||||||||||||
| Location | Chr 7: 99.31 - 99.31 Mb | Chr 16: 19.52 - 19.52 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Olfactory receptor, family 2, subfamily AE, member 1, also known as OR2AE1, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
Further reading
- (1999) "Toward a complete human genome sequence.". Genome Res. 8 (11): 1097-108. PMID 9847074.
- Thompson EE, Kuttab-Boulos H, Yang L, et al. (2006). "Sequence diversity and haplotype structure at the human CYP3A cluster.". Pharmacogenomics J. 6 (2): 105-14. doi:10.1038/sj.tpj.6500347. PMID 16314882.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub
G protein-coupled receptors: olfactory receptors | |
|---|---|
| Family 1 | A1 - A2 - B1 - C1 - D2 - D4 - D5 - E1 - E2 - F1 - F2 - G1 - I1 - J1 - J2 - J4 - K1 - L1 - L3 - L4 - L6 - L8 - M1 - N1 - N2 - Q1 - S1 - S2 |
| Family 2 | A2 - A4 - A5 - A7 - A12 - A14 - A25 - A42 - AE1 - AG1 - AG2 - AJ1 - AK2 - AP1 - AT4 - B2 - B3 - B6 - B8 - B11 - C1 - C3 - D2 - D3 - F1 - F2 - G2 - G3 - G6 - H1 - H2 - J1 - J2 - J3 - K2 - L2 - L3 - L5 - L8 - L13 - M2 - M3 - M4 - M5 - M7 - S2 - T1 - T2 - T3 - T4 - T5 - T6 - T8 - T10 - T11 - T12 - T27 - T29 - T33 - T34 - T35 - V1 - V2 - W1 - W3 - W5 - Y1 - Z1 |
| Family 3 | A1 - A2 - A3 - A4 |
| Family 4 | A5 - A15 - A16 - A47 - B1 - C3 - C5 - C6 - C11 - C12 - C13 - C15 - C16 - C45 - C46 - D1 - D2 - D5 - D6 - D9 - D10 - D11 - E2 - F4 - F5 - F6 - F15 - F17 - F21 - F29 - K1 - K2 - K3 - K5 - K13 - K14 - K15 - K17 - L1 - M1 - M2 - N2 - N4 - N5 - P4 - Q3 - S1 - S2 - X1 - X2 |
| Family 5 | A1 - A2 - AC2 - AK2 - AK3 - AN1 - AP2 - AR1 - AS1 - AT1 - AU1 - AY1 - B2 - B3 - B12 - B17 - B21 - BF1 - BU1 - C1 - D13 - D14 - D16 - D18 - F1 - H1 - H2 - H6 - H14 - H15 - I1 - J2 - K1 - K2 - K3 - K4 - L1 - L2 - M1 - M3 - M8 - M9 - M10 - M11 - P2 - P3 - R1 - T1 - T2 - T3 - U1 - V1 - W2 |
| Family 6 | A2 - B1 - B2 - B3 - C1 - C2 - C3 - C4 - C6 - C65 - C68 - C70 - C74 - C75 - C76 - F1 - J1 - K2 - K3 - K6 - M1 - N1 - N2 - P1 - Q1 - S1 - T1 - V1 - X1 - Y1 |
| Family 7 | A2 - A5 - A10 - A17 - C1 - C2 - D2 - D4 - E24 - G1 - G2 - G3 |
| Family 8 | A1 - B2 - B3 - B4 - B8 - B12 - D1 - D2 - D4 - G1 - G2 - G5 - H1 - H2 - H3 - I2 - J1 - J3 - K1 - K3 - K5 - S1 - U1 |
| Family 9 | A2 - A4 - G1 - G4 - I1 - K2 - Q1 - Q2 |
| Family 10 | A2 - A3 - A4 - A5 - A6 - A7 - AD1 - C1 - D4 - G2 - G3 - G4 - G6 - G7 - G8 - G9 - H1 - H2 - H3 - H4 - H5 - J1 - J3 - J5 - J6 - K1 - K2 - P1 - Q1 - R2 - S1 - T2 - V1 - W1 - X1 - Z1 |
| Family 11 | A1 - G2 - H1 - H4 - H6 - L1 |
| Family 12 | D2 - D3 |
| Family 13 | A1 - C2 - C3 - C4 - C5 - C8 - C9 - D1 - F1 - G1 - H1 - J1 |
| Family 17 | -1 |
| Family 51 | A2 - A4 - A7 - B2 - B4 - B5 - B6 - D1 - E1 - E2 - F1 - F2 - G1 - G2 - H1 - I1 - I2 - L1 - M1 - Q1 - S1 - T1 - V1 |
| Family 52 | A1 - A4 - A5 - B2 - B4 - B6 - D1 - E1 - E2 - E4 - E5 - E6 - E8 - H1 - I1 - I2 - J3 - K1 - K2 - L1 - L2 - M1 - N1 - N2 - N4 - N5 - P1 - R1 - W1 |
| Family 56 | A1 - A3 - A4 - B1 - B4 |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
