Small cell carcinoma
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| Small cell carcinoma Classification and external resources | |
 | |
|---|---|
| Histopathologic image of small cell carcinoma of the lung. CT-guided core needle biopsy. H & E stain. | |
| ICD-O: | M8041/3 |
| MedlinePlus | 000122 |
| eMedicine | med/1336 |
| MeSH | D018288 |
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Overview
Small cell carcinoma is a type of carcinoma usually associated with the lung, though it can be associated with other topographies, such as in cervical cancer.
Types
When associated with the lung, it is sometimes called "oat cell carcinoma" due to the flat cell shape and scanty cytoplasm. It originates from neuroendocrine cells in the bronchus and often leads to ectopic production of hormones ADH and ACTH. It is the most widely metastatic of all tumors (and henced staged differently) and is sometimes seen in combination with squamous cell carcinomas. Smoking is a significant etiological factor. Symptoms and signs are as for other lung cancers.
In the prostate, small cell carcinoma is a rare form of cancer. Due to the fact that there is little variation in prostate specific antigen levels, this form of cancer is normally diagnosed at an advanced stage.
Pathological Findings
 NERVOUS SYSTEM: Brain: Meningeal Carcinomatosis: Micro low mag H&E masses of small cell carcinoma in meninges oat cell from lung |
 MALE REPRODUCTIVE: Prostate: Adenocarcinoma: Micro low mag H&E diffusely infiltrating small cell carcinoma readily seen |
 CERVIX, VULVA, VAGINA: SMALL CELL CARCINOMA The tumor is characterized by a diffuse infiltration of small round cells with scant cytoplasm and hyperchromatic nuclei. |
 CERVIX, VULVA, VAGINA: SMALL CELL CARCINOMA This high magnification of the tumor shows a relatively uniform population of small cells and an occasional cell with a large round nucleus. |
See also
References
External links
- Neuroimmunology - by Abid R Karim, Birmingham UK, at University of Birmingham Medical School
- Image at Tulane University
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
