Odynophagia

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Odynophagia

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884

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Odynophagia is defined as painful swallowing.

  • Dysphagia is defined as difficulty in swallowing
  • Dysphagia is usually due to muscle or nerve control

Diagnosis

History and Symptoms

  • Onset
  • Severity
  • Duration
  • Dysphagia with liquids versus solids
  • Psychiatric history
  • Prior episodes
  • Substance exposure
  • History of neck and head problems

Laboratory Findings

Electrolyte and Biomarker Studies

  • Creatinine phosphokinase (CPK) can be used to rule out cardiac ischemia as a cause.

Electrocardiogram

Can be used to assess for left atrial enlargement.

Chest X Ray

Can used to rule out lung cancer and other mass lesions as well as left atrial enlargement.

MRI and CT

  • MRI of brain can be used to exclude CVA and mass lesions of the head and neck.

Echocardiography or Ultrasound

Can be used to rule out an aneurysm or left atrial enlargement as a cause.

Other Diagnostic Studies

Differential Diagnosis

In alphabetical order. [1] [1]

Treatment

  • Endoscopy (acute and chronic mechanical obstructions)
  • Speech therapy (ALS and stroke patients)

Pharmacotherapy

  • Proton pump inhibitors or promotility agents, weight loss, avoidance of offending foods (gastroesophageal reflux disease)
  • Anticholinergics (ALS, stroke, lower esophageal spasms)
  • Muscarinic agents (myasthenia gravis)
  • Glucocorticoids (myasthenia gravis and polymyositis)
  • Antispasmodics, botulinum toxin injection (lower esophageal spasm)

Surgery and Device Based Therapy

  • Thoracic surgery, possible balloon dilation (chronic mechanical obstruction)

References

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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