Papaveretum

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Overview

Papaveretum (BAN) is a preparation containing a mixture of hydrochloride salts of opium alkaloids. Since 1993, papaveretum has been defined in the British Pharmacopoeia (BP) as a mixture of 253 parts morphine hydrochloride, 23 parts papaverine hydrochloride, and 20 parts codeine hydrochloride (Sweetman, 2004). It is commonly marketed under the trade name Omnopon®.

Although relatively uncommon, with the wide availability of single-component opiates and synthetic opioids, papaveretum is still used for moderate to severe pain and for pre-operative sedation. In the clinical setting, papaveretum is usually given by the subcutaneous, intramuscular or intravenous routes.

Prior to 1993, the preparation also contained noscapine, however this was removed from the BP formulation due to the genotoxic potential of noscapine.

See also

• Morphine
• Papaverine
• Codeine

External links

• N02AA10

References

• (November 30, 2004) in Edited by Sean C. Sweetman: Martindale: The complete drug reference, 34th edition, London: Pharmaceutical Press. ISBN 0-85369-550-4. 

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .