Organum vasculosum of the lamina terminalis
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
| Brain: Organum vasculosum of the lamina terminalis | ||
|---|---|---|
| NeuroNames | hier-366 | |
| Dorlands/Elsevier | o_06/12596306 | |
The organum vasculosum of the lamina terminalis (OVLT) (or supraoptic crest) is one of the circumventricular organs of the brain . Other circumventricular organs are the subfornical organ (SFO) and the area postrema in the brainstem. The OVLT and the SFO are both strongly interconnected with the median preoptic nucleus of the hypothalamus (the nucleus medianus), and together these three structures comprise the so called "AV3V" region - the region anterior and ventral to the third ventricle. The AV3V region is very important in the regulation of fluid and electrolyte balance, by controlling thirst, sodium excretion, blood volume regulation, and vasopressin secretion.
The OVLT is outside the blood brain barrier, and so neurons in this region can respond to factors that are present in the systemic circulation.
Some neurons in the OVLT are osmoreceptors, being sensitive to the osmotic pressure of the blood. These neurons project to the supraoptic nucleus and paraventricular nucleus to regulate the activity of vasopressin-secreting neurons. These neurons also project to the nucleus medianus (also called the medial preoptic nucleus) which is involved in controlling thirst.
External links
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
