Orlistat instructions for administration
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
Instructions for administration
Recommended dose
Nutritional Balance
Effects with Xenical above 120mg
Recommended dose
The recommended dose of XENICAL is one 120- mg capsule three times a day with each
main meal containing fat (during or up to 1 hour after the meal). Return to top
Nutritional Balance
The patient should be on a nutritionally balanced, reduced-calorie diet that contains
approximately 30% of calories from fat. The daily intake of fat, carbohydrate, and protein
should be distributed over three main meals. If a meal is occasionally missed or contains
no fat, the dose of XENICAL can be omitted. Because XENICAL has been shown to reduce the absorption of some fat-soluble vitamins and beta-carotene, patients should be counseled to take a multivitamin
containing fat-soluble vitamins to ensure adequate nutrition. The supplement should be taken at least 2 hours before or after the administration of XENICAL, such as at bedtime. Return to top
Effects with Xenical above 120mg
Doses above 120 mg three times a day have not been shown to provide additional benefit.
Based on fecal fat measurements, the effect of XENICAL is seen as soon as 24 to 48
hours after dosing. Upon discontinuation of therapy, fecal fat content usually returns to
pretreatment levels within 48 to 72 hours. Return to top
The content of this page is taken from the FDA package insert for this drug and should not be edited.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
