Normoblast
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| Normoblast Classification and external resources | |
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| Bone Marrow: Multilobulated Normoblast. Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
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Overview
An erythroblast is a type of red blood cell which still retains a cell nucleus. It is the immediate precursor of a normal erythrocyte.
Nomenclature
The term normoblast is sometimes used as a synonym for erythroblast, but at other times it is considered a subcategory. In the latter context, there are two types of erythroblasts:
- "normoblasts" - develop as expected
- "megaloblasts" - an unusually large erythroblast that can be associated with pernicious anemia and folic acid deficiency (collectively called megaloblastic anemia)
Development
There are four stages in the development of a normoblast.
| Image | Description |
 | Pronormoblast |
 | Basophilic normoblast |
 | Polychromatic normoblast (also polychromatophilic) |
 | Orthochromatic normoblast (also orthochromatophilic) |
Additional images
 Blood cell lineage |
 Hematopoiesis |
 Blood: Schistocytes: Micro blood film shows an excellent example with normoblast. |
See also
External links
- Pronormoblasts Presented by the University of Virginia
- Basophilic Normoblasts Presented by the University of Virginia
- Polychromatophilic Normoblasts Presented by the University of Virginia
- Orthochromatic Normoblasts Presented by the University of Virginia
- n_10/12578105 at Dorland's Medical Dictionary - "normoblast"
- e_15/12341680 at Dorland's Medical Dictionary - "erythroblast"
- normoblast at eMedicine Dictionary
- MeSH Normoblasts
- Histology at BU 01804loa - "Bone Marrow and Hemopoiesis bone marrow smear, erythroblast series with proerythroblast "
- Histology at uiowa.edu
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
