Ostium primum
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| Ostium primum | ||
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| Interior of dorsal half of heart from a human embryo of about thirty days. (Ostium primum visible below septum primum, but not labeled.) | ||
| Gray's | subject #135 512 | |
| Dorlands/Elsevier | o_09/12602009 | |
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In the developing heart, for a time the atria communicate with each other by an opening between the free edge of the septum primum and the AV cushions, known as the ostium primum (interatrial foramen primum), below the free margin of the septum.
Closing of ostium primum
This opening is closed by the union of the septum primum with the septum intermedium, and the communication between the atria is reëstablished through an opening which is developed in the upper part of the septum primum; this opening is (confusingly) known as the foramen secundum.
A second entity, the septum secundum, develops to the right of the septum primum and the opening between the upper and lower limbs of the septum secundum is known as the foramen ovale of the heart and persists until birth.
These two septae fuse later in life, to complete the formation of the atrial septum.
Clinical significance
Failure to fuse can lead to an ostium primum atrial septal defect.[1] This is the most common type of atrial septal defect.[1]
References
External links
- Embryology at Temple Heart98/heart97a/sld036
- Overview and diagram at um.edu.mt
- MedEd at Loyola GrossAnatomy/thorax0/Heart_Development/Atria.html
This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant.
Prenatal development/Mammalian development of circulatory system | |
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| Vascular | Blood island
arteries: Dorsal aorta - Aortic arches - Vitelline arteries - Ductus arteriosus - Umbilical artery |
| Heart development | Primitive heart tube: Truncus arteriosus - Bulbus cordis - Primitive ventricle - Primitive atrium - Sinus venosus Septum primum (Ostium primum, Ostium secundum) - Septum secundum (Foramen ovale) - other septa (Endocardial cushions/Septum intermedium, Aorticopulmonary septum) - Atrial canal |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
