Oxybuprocaine
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| Image:Oxybuprocaine.svg | |
| Oxybuprocaine
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| Systematic (IUPAC) name | |
| 2-diethylaminoethyl 4-amino-3-butoxy-benzoate | |
| Identifiers | |
| CAS number | |
| ATC code | D04 S01HA02 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C17H29ClN2O3 |
| Mol. mass | 344.877 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
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Overview
Oxybuprocaine is the name of a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine is sold by Novartis under the brand names Novesine or Novesin.
Where oxybuprocaine is used specifically
- In ophthalmology in order to numb the surface of the eye (the outermost layers of the cornea and conjunctiva) for the following purposes:
- In order to perform a contact/applanation tonometry.
- In order to remove small foreign objects from the uppermost layer of the cornea or conjunctiva.
- In otolaryngology for numbing the mucous membranes of the nostrils.
Topical anesthetics in general
Oxybuprocaine like any other topical anesthetic used in the eye (like for example tetracaine, proxymetacaine and proparacaine) can cause irreversible corneal damage and even complete destruction of the cornea when used excessively (excessive use means several times a day during several days or even weeks).
See also
Antipruritics (D04) | |
|---|---|
| Antihistamines for topical use | Thonzylamine - Mepyramine - Thenalidine - Tripelennamine - Chloropyramine - Promethazine - Tolpropamine - Dimetindene - Clemastine - Bamipine - Isothipendyl - Diphenhydramine - Chlorphenoxamine |
| Anesthetics for topical use | Lidocaine - Cinchocaine - Oxybuprocaine - Benzocaine - Quinisocaine - Tetracaine - Pramocaine |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
