para-Aminohippurate

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Para-Aminohippurate
Image:P-Aminohippurate sodium.svg
IUPAC name	sodium 2-[(4-aminobenzoyl)amino]acetate
Identifiers
CAS number
PubChem	7178
SMILES	C1=CC(=CC=C1C(=O)NCC(=O)[O-])N.[Na+]
Properties
Molecular formula	C9H9N2NaO3
Molar mass	216.169 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

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para-Aminohippurate (PAH) is a substance used in the measurement of renal blood flow. It is useful in this measurement because it is primarily secreted by the renal tubules; only 20-30% is filtered by the glomerulus.^[1]

The renal extraction ratio of PAH is a normal individual is approximately 0.92.^[1]

References

Further reading

• PAH clearance

External links

• "Effect of 20,60 and 120 minutes of renal ischemia on glomerular and tubular function" (subscription may be necessary)
• "Glomerular filtration rate, renal blood flow and blood viscosity during and after diabetic coma" (subscription may be necessary)

v • d • e Urinary system, physiology: renal physiology and acid base physiology
Filtration	Renal blood flow - Ultrafiltration - Countercurrent exchange
Hormones affecting filtration	Antidiuretic hormone (ADH) - Aldosterone - Atrial natriuretic peptide
Secretion/clearance	Pharmacokinetics - Clearance of medications
Reabsorption	Solvent drag -Na+ - Cl- -urea -glucose -oligopeptides -protein
Endocrine	Renin - Erythropoietin (EPO) - Calcitriol (Active vitamin D) - Prostaglandins
Assessing Renal function / Measures of dialysis	Glomerular filtration rate - Creatinine clearance - Renal clearance ratio - Urea reduction ratio - Kt/V - Standardized Kt/V - Hemodialysis product - PAH clearance (Effective renal plasma flow - Extraction ratio)
Acid base physiology	Fluid balance - Darrow Yannet diagram - Body water - Interstitial fluid - Extracellular fluid - Intracellular fluid/Cytosol - Plasma - Transcellular fluid - Base excess - Davenport diagram - Anion gap - Arterial blood gas
Buffering/compensation	Bicarbonate buffering system - Respiratory compensation - Renal compensation

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .