Parahippocampal gyrus

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Parahippocampal gyrus
Medial surface of left cerebral hemisphere. ("Hippocampal gyrus" visible near bottom.)
Parahippocampal gyrus labeled at bottom center.
Latin gyrus parahippocampalis
MeSH Parahippocampal+Gyrus
Dorlands/Elsevier g_13/14816442

The parahippocampal gyrus (or hippocampal gyrus) is a grey matter cortical region of the brain that surrounds the hippocampus. This region plays an important role in memory encoding and retrieval. The anterior part of the gyrus includes the perirhinal and entorhinal cortices. The term parahippocampal cortex is used to refer to an area that encompasses both the posterior portion of the parahippocampal gyrus and the medial portion of the fusiform gyrus.


The parahippocampal place area (PPA) is a subregion of the parahippocampal cortex that plays an important role in the encoding and recognition of scenes (rather than faces or objects). fMRI studies indicate that this region of the brain becomes highly active when human subjects view topographical scene stimuli such as images of landscapes, cityscapes, or rooms (i.e. images of "places"). The region was first described by Russell Epstein (currently at the University of Pennsylvania) and Nancy Kanwisher (currently at MIT) in 1998 ([1], see also other similar reports by Geoffrey Aguirre [2] and Alumit Ishai [3]). Damage to the PPA (for example, due to stroke) often leads to a syndrome in which patients cannot visually recognize scenes even though they can recognize the individual objects in the scenes (such as people, furniture, etc.). The PPA is often considered the complement of the fusiform face area (FFA), a nearby cortical region that responds strongly whenever faces are viewed, and which is believed to be important for face recognition.

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nl:Parahippocampale cortex
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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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