Pneumotaxic center

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Pneumotaxic center

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The pneumotaxic center, also known as the pontine respiratory group (PRG), is a network of neurons in the rostral dorsal lateral pons. It consists of the Kölliker-Fuse nucleus and the medial parabrachial nucleus.[1]

Respiratory effects

The PRG antagonises the apneustic center, cyclically inhibiting inspiration. The PRG limits the burst of action potentials in the phrenic nerve, effectively decreasing the tidal volume and regulating the respiratory rate. Absence of the PRG results in an increase in depth of respiration and a decrease in respiratory rate.

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References

  1. Levitzky, Michael G. (2002). Pulmonary Physiology, 6th edition. McGraw-Hill Professional, 193-4. ISBN 007138765X. 
  2. Costanzo, Linda S. (2006). Physiology, 3rd edition. Philadelphia, PA: Elsevier, 224. ISBN 978-1-4160-2320-3. 
  3. Roger Shannon, David M. Baekey, Kendall F. Morris, Sarah C. Nuding, Lauren S. Segers and Bruce G. Lindsey (2004). "Pontine respiratory group neuron discharge is altered during fictive cough in the decerebrate cat". Respiratory Physiology & Neurobiology 142 (1): 43-54. doi:10.1016/j.resp.2004.05.002.
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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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